BDBM480928 8-oxa-2-azaspiro[4.5]dec l{2-[(pyrazin-2-ylmethyl)amino]pyrimidin-5-yl}methanone::US10906888, Example 142::US20240083873, Compound A::US20240124479, Compound A

SMILES: c1cnc(cn1)CNc2ncc(cn2)C(=O)N3CCC4(C3)CCOCC4

InChI Key: InChIKey=VGRLXWFIXGZRMS-UHFFFAOYSA-N

Data: 10 IC50

PDB links: 1 PDB ID matches this monomer.

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 480928   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Pantetheinase (Human)	BDBM480928 (8-oxa-2-azaspiro[4.5]dec l{2-[(pyrazin-2-ylmethyl)...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	7.66	n/a	n/a	n/a	n/a	n/a	n/a
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Pantetheinase (Human)	BDBM480928 (8-oxa-2-azaspiro[4.5]dec l{2-[(pyrazin-2-ylmethyl)...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	11.2	n/a	n/a	n/a	n/a	n/a	n/a
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Pantetheinase (Human)	BDBM480928 (8-oxa-2-azaspiro[4.5]dec l{2-[(pyrazin-2-ylmethyl)...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	11.2	n/a	n/a	n/a	n/a	n/a	n/a
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Pantetheinase (Human)	BDBM480928 (8-oxa-2-azaspiro[4.5]dec l{2-[(pyrazin-2-ylmethyl)...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	6.90	n/a	n/a	n/a	n/a	n/a	n/a
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Pantetheinase (Mouse)	BDBM480928 (8-oxa-2-azaspiro[4.5]dec l{2-[(pyrazin-2-ylmethyl)...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	25	n/a	n/a	n/a	n/a	n/a	n/a
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Pantetheinase (Human)	BDBM480928 (8-oxa-2-azaspiro[4.5]dec l{2-[(pyrazin-2-ylmethyl)...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	9	n/a	n/a	n/a	n/a	n/a	n/a
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Biotinidase (Human)	BDBM480928 (8-oxa-2-azaspiro[4.5]dec l{2-[(pyrazin-2-ylmethyl)...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Pantetheinase (Mouse)	BDBM480928 (8-oxa-2-azaspiro[4.5]dec l{2-[(pyrazin-2-ylmethyl)...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	53	n/a	n/a	n/a	n/a	n/a	n/a
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Vanin 1 (Rat)	BDBM480928 (8-oxa-2-azaspiro[4.5]dec l{2-[(pyrazin-2-ylmethyl)...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	12	n/a	n/a	n/a	n/a	n/a	n/a
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Potassium voltage-gated channel subfamily H member 2 (Human)	BDBM480928 (8-oxa-2-azaspiro[4.5]dec l{2-[(pyrazin-2-ylmethyl)...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>100	n/a	n/a	n/a	n/a	n/a	n/a
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