BDBM4810 (3Z)-3-[(3,5-dimethyl-1H-pyrrol-2-yl)methylidene]-2,3-dihydro-1H-indol-2-one::3-[(2,4-dimethylpyrrol-5-yl)methylidenyl]-indolin-2-one::CHEMBL276711::SU5146::SU5416::Semaxanib::US10189853, semaxanib::US11111252, Compound SU5416::US9422297, SU5416::cid_5329098

SMILES: Cc1cc(C)c(\C=C2/C(=O)Nc3ccccc23)[nH]1

InChI Key: InChIKey=WUWDLXZGHZSWQZ-UHFFFAOYSA-N

Data: 81 IC50  6 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 87 hits for monomerid = 4810   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Macrophage colony-stimulating factor 1 receptor (Human)	BDBM4810 (cid_5329098 | CHEMBL276711 | SU5146 | (3Z)-3-[(3,5...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	84	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tyrosine-protein kinase ABL1 (Human)	BDBM4810 (cid_5329098 | CHEMBL276711 | SU5146 | (3Z)-3-[(3,5...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 1 (Human)	BDBM4810 (cid_5329098 | CHEMBL276711 | SU5146 | (3Z)-3-[(3,5...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	43	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 3 (Human)	BDBM4810 (cid_5329098 | CHEMBL276711 | SU5146 | (3Z)-3-[(3,5...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase Src (Human)	BDBM4810 (cid_5329098 | CHEMBL276711 | SU5146 | (3Z)-3-[(3,5...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Human)	BDBM4810 (cid_5329098 | CHEMBL276711 | SU5146 | (3Z)-3-[(3,5...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	884	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 1 (Human)	BDBM4810 (cid_5329098 | CHEMBL276711 | SU5146 | (3Z)-3-[(3,5...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Insulin-like growth factor 1 receptor (Human)	BDBM4810 (cid_5329098 | CHEMBL276711 | SU5146 | (3Z)-3-[(3,5...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Mast/stem cell growth factor receptor Kit (Human)	BDBM4810 (cid_5329098 | CHEMBL276711 | SU5146 | (3Z)-3-[(3,5...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	660	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Angiopoietin-1 receptor (Human)	BDBM4810 (cid_5329098 | CHEMBL276711 | SU5146 | (3Z)-3-[(3,5...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Macrophage-stimulating protein receptor (Human)	BDBM4810 (cid_5329098 | CHEMBL276711 | SU5146 | (3Z)-3-[(3,5...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Human)	BDBM4810 (cid_5329098 | CHEMBL276711 | SU5146 | (3Z)-3-[(3,5...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Human)	BDBM4810 (cid_5329098 | CHEMBL276711 | SU5146 | (3Z)-3-[(3,5...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Human)	BDBM4810 (cid_5329098 | CHEMBL276711 | SU5146 | (3Z)-3-[(3,5...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.79E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 1 (Human)	BDBM4810 (cid_5329098 | CHEMBL276711 | SU5146 | (3Z)-3-[(3,5...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Human)	BDBM4810 (cid_5329098 | CHEMBL276711 | SU5146 | (3Z)-3-[(3,5...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 1 (Human)	BDBM4810 (cid_5329098 | CHEMBL276711 | SU5146 | (3Z)-3-[(3,5...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Human)	BDBM4810 (cid_5329098 | CHEMBL276711 | SU5146 | (3Z)-3-[(3,5...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.22E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Mast/stem cell growth factor receptor Kit (Human)	BDBM4810 (cid_5329098 | CHEMBL276711 | SU5146 | (3Z)-3-[(3,5...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	35	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Human)	BDBM4810 (cid_5329098 | CHEMBL276711 | SU5146 | (3Z)-3-[(3,5...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	220	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Human)	BDBM4810 (cid_5329098 | CHEMBL276711 | SU5146 | (3Z)-3-[(3,5...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.43E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Human)	BDBM4810 (cid_5329098 | CHEMBL276711 | SU5146 | (3Z)-3-[(3,5...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 3 (Human)	BDBM4810 (cid_5329098 | CHEMBL276711 | SU5146 | (3Z)-3-[(3,5...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	500	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Human)	BDBM4810 (cid_5329098 | CHEMBL276711 | SU5146 | (3Z)-3-[(3,5...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Human)	BDBM4810 (cid_5329098 | CHEMBL276711 | SU5146 | (3Z)-3-[(3,5...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Human)	BDBM4810 (cid_5329098 | CHEMBL276711 | SU5146 | (3Z)-3-[(3,5...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.29E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Human)	BDBM4810 (cid_5329098 | CHEMBL276711 | SU5146 | (3Z)-3-[(3,5...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Human)	BDBM4810 (cid_5329098 | CHEMBL276711 | SU5146 | (3Z)-3-[(3,5...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Human)	BDBM4810 (cid_5329098 | CHEMBL276711 | SU5146 | (3Z)-3-[(3,5...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Human)	BDBM4810 (cid_5329098 | CHEMBL276711 | SU5146 | (3Z)-3-[(3,5...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Human)	BDBM4810 (cid_5329098 | CHEMBL276711 | SU5146 | (3Z)-3-[(3,5...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 1 (Human)	BDBM4810 (cid_5329098 | CHEMBL276711 | SU5146 | (3Z)-3-[(3,5...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Human)	BDBM4810 (cid_5329098 | CHEMBL276711 | SU5146 | (3Z)-3-[(3,5...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
ALK tyrosine kinase receptor (Human)	BDBM4810 (cid_5329098 | CHEMBL276711 | SU5146 | (3Z)-3-[(3,5...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.81E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor alpha (Human)	BDBM4810 (cid_5329098 | CHEMBL276711 | SU5146 | (3Z)-3-[(3,5...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Human)	BDBM4810 (cid_5329098 | CHEMBL276711 | SU5146 | (3Z)-3-[(3,5...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	400	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Human)	BDBM4810 (cid_5329098 | CHEMBL276711 | SU5146 | (3Z)-3-[(3,5...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Human)	BDBM4810 (cid_5329098 | CHEMBL276711 | SU5146 | (3Z)-3-[(3,5...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.29E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Human)	BDBM4810 (cid_5329098 | CHEMBL276711 | SU5146 | (3Z)-3-[(3,5...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.29E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Human)	BDBM4810 (cid_5329098 | CHEMBL276711 | SU5146 | (3Z)-3-[(3,5...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.29E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase receptor Ret (Human)	BDBM4810 (cid_5329098 | CHEMBL276711 | SU5146 | (3Z)-3-[(3,5...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	170	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
ALK tyrosine kinase receptor (Human)	BDBM4810 (cid_5329098 | CHEMBL276711 | SU5146 | (3Z)-3-[(3,5...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tyrosine-protein kinase ABL1 (Human)	BDBM4810 (cid_5329098 | CHEMBL276711 | SU5146 | (3Z)-3-[(3,5...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.10E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Receptor-type tyrosine-protein kinase FLT3 (Human)	BDBM4810 (cid_5329098 | CHEMBL276711 | SU5146 | (3Z)-3-[(3,5...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	160	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Human)	BDBM4810 (cid_5329098 | CHEMBL276711 | SU5146 | (3Z)-3-[(3,5...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	12.9	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Human)	BDBM4810 (cid_5329098 | CHEMBL276711 | SU5146 | (3Z)-3-[(3,5...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.29E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Human)	BDBM4810 (cid_5329098 | CHEMBL276711 | SU5146 | (3Z)-3-[(3,5...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	8.02E+4	n/a	n/a	n/a	n/a	7.5	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Human)	BDBM4810 (cid_5329098 | CHEMBL276711 | SU5146 | (3Z)-3-[(3,5...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.66E+4	n/a	n/a	n/a	n/a	7.5	n/a
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Oxytocin receptor (Human)	BDBM4810 (cid_5329098 | CHEMBL276711 | SU5146 | (3Z)-3-[(3,5...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	1.15E+4	n/a	n/a	n/a	n/a
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Vasopressin V1a receptor (Human)	BDBM4810 (cid_5329098 | CHEMBL276711 | SU5146 | (3Z)-3-[(3,5...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	1.21E+4	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair