BDBM4813 N-[2-(diethylamino)ethyl]-2,4-dimethyl-5-{[(3Z)-2-oxo-2,3-dihydro-1H-indol-3-ylidene]methyl}-1H-pyrrole-3-carboxamide::SU11248 analog 12a

SMILES: CCN(CC)CCNC(=O)c1c(C)[nH]c(\C=C2/C(=O)Nc3ccccc23)c1C

InChI Key: InChIKey=UJGXTMZILSGDLG-UHFFFAOYSA-N

Data: 6 IC50

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Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 4813   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Vascular endothelial growth factor receptor 2 (Human)	BDBM4813 (N-[2-(diethylamino)ethyl]-2,4-dimethyl-5-{[(3Z)-2-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	50	n/a	n/a	n/a	n/a	7.5	22
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Fibroblast growth factor receptor 1 (Human)	BDBM4813 (N-[2-(diethylamino)ethyl]-2,4-dimethyl-5-{[(3Z)-2-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	880	n/a	n/a	n/a	n/a	7.5	22
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Platelet-derived growth factor receptor beta (Human)	BDBM4813 (N-[2-(diethylamino)ethyl]-2,4-dimethyl-5-{[(3Z)-2-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	17	n/a	n/a	n/a	n/a	n/a	n/a
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Epidermal growth factor receptor (Human)	BDBM4813 (N-[2-(diethylamino)ethyl]-2,4-dimethyl-5-{[(3Z)-2-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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5'-AMP-activated protein kinase catalytic subunit alpha-1 (Human)	BDBM4813 (N-[2-(diethylamino)ethyl]-2,4-dimethyl-5-{[(3Z)-2-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	246	n/a	n/a	n/a	n/a	n/a	n/a
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5'-AMP-activated protein kinase catalytic subunit alpha-2 (Human)	BDBM4813 (N-[2-(diethylamino)ethyl]-2,4-dimethyl-5-{[(3Z)-2-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	89	n/a	n/a	n/a	n/a	n/a	n/a
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