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BDBM4837 1-[2-amino-6-(2,4,6-trimethylphenyl)pyrido[2,3-d]pyrimidin-7-yl]-3-tert-butylurea::PD089828 analog 18

SMILES: Cc1cc(C)c(c(C)c1)-c1cc2cnc(N)nc2nc1NC(=O)NC(C)(C)C

InChI Key: InChIKey=SMLFOSIGUQORAV-UHFFFAOYSA-N

Data: 4 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 4837
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Platelet-derived growth factor receptor beta (Human)	BDBM4837 (1-[2-amino-6-(2,4,6-trimethylphenyl)pyrido[2,3-d]p...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.47E+3	n/a	n/a	n/a	n/a	7.4	25
TBA									Citation and Details
TBA					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 1 (Human)	BDBM4837 (1-[2-amino-6-(2,4,6-trimethylphenyl)pyrido[2,3-d]p...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	270	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
TBA					More data for this Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase Src (Human)	BDBM4837 (1-[2-amino-6-(2,4,6-trimethylphenyl)pyrido[2,3-d]p...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	360	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
TBA					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor alpha/beta (Human)	BDBM4837 (1-[2-amino-6-(2,4,6-trimethylphenyl)pyrido[2,3-d]p...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.47E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
TBA					More data for this Ligand-Target Pair