BindingDB PrimarySearch

BDBM4851 (4-chlorophenyl)-[4-(4-pyridylmethyl)phthalazin-1-yl]amine::(A) PTK787::CGP 79787::CHEMBL101253::CHEMBL75232::N-(4-chlorophenyl)-4-(pyridin-4-ylmethyl)-1-phthalazinamine::N-(4-chlorophenyl)-4-(pyridin-4-ylmethyl)phthalazin-1-amine::PTK-787::PTK787::ZK222584::cid_151194

SMILES: Clc1ccc(Nc2nnc(Cc3ccncc3)c3ccccc23)cc1

InChI Key: InChIKey=YCOYDOIWSSHVCK-UHFFFAOYSA-N

Data: 3 KI 79 IC50 778 Kd

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 860 hits for monomerid = 4851
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Vascular endothelial growth factor receptor 1 (Human)	BDBM4851 (cid_151194 \| PTK787 \| CHEMBL101253 \| N-(4-chloroph...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	77	n/a	n/a	n/a	n/a	7.5	22
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Vascular endothelial growth factor receptor 2 (Human)	BDBM4851 (cid_151194 \| PTK787 \| CHEMBL101253 \| N-(4-chloroph...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	37	n/a	n/a	n/a	n/a	n/a	n/a
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Vascular endothelial growth factor receptor 2 (Human)	BDBM4851 (cid_151194 \| PTK787 \| CHEMBL101253 \| N-(4-chloroph...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	54	n/a	n/a	n/a	n/a	7.5	22
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Vascular endothelial growth factor receptor 1 (Human)	BDBM4851 (cid_151194 \| PTK787 \| CHEMBL101253 \| N-(4-chloroph...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	140	n/a	n/a	n/a	n/a	n/a	n/a
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Macrophage colony-stimulating factor 1 receptor (Human)	BDBM4851 (cid_151194 \| PTK787 \| CHEMBL101253 \| N-(4-chloroph...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	n/a	18	n/a	n/a	n/a	7.4	25
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Epithelial discoidin domain-containing receptor 1 (Human)	BDBM4851 (cid_151194 \| PTK787 \| CHEMBL101253 \| N-(4-chloroph...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	n/a	270	n/a	n/a	n/a	7.4	25
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Vascular endothelial growth factor receptor 1 (Human)	BDBM4851 (cid_151194 \| PTK787 \| CHEMBL101253 \| N-(4-chloroph...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	n/a	9.60	n/a	n/a	n/a	7.4	25
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Vascular endothelial growth factor receptor 3 (Human)	BDBM4851 (cid_151194 \| PTK787 \| CHEMBL101253 \| N-(4-chloroph...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	n/a	330	n/a	n/a	n/a	7.4	25
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Tyrosine-protein kinase FRK (Human)	BDBM4851 (cid_151194 \| PTK787 \| CHEMBL101253 \| N-(4-chloroph...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	n/a	1.80E+3	n/a	n/a	n/a	7.4	25
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Platelet-derived growth factor receptor alpha (Human)	BDBM4851 (cid_151194 \| PTK787 \| CHEMBL101253 \| N-(4-chloroph...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	n/a	96	n/a	n/a	n/a	n/a	n/a
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Platelet-derived growth factor receptor beta (Human)	BDBM4851 (cid_151194 \| PTK787 \| CHEMBL101253 \| N-(4-chloroph...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	n/a	25	n/a	n/a	n/a	n/a	n/a
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Proto-oncogene tyrosine-protein kinase receptor Ret [1-999,M918T] (Human)	BDBM4851 (cid_151194 \| PTK787 \| CHEMBL101253 \| N-(4-chloroph...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	n/a	7.60E+3	n/a	n/a	n/a	n/a	n/a
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Vascular endothelial growth factor receptor 2 (Human)	BDBM4851 (cid_151194 \| PTK787 \| CHEMBL101253 \| N-(4-chloroph...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	n/a	62	n/a	n/a	n/a	n/a	n/a
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Citron Rho-interacting kinase (Human)	BDBM4851 (cid_151194 \| PTK787 \| CHEMBL101253 \| N-(4-chloroph...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	n/a	8.80E+3	n/a	n/a	n/a	n/a	n/a
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Protein-tyrosine kinase 6 (Human)	BDBM4851 (cid_151194 \| PTK787 \| CHEMBL101253 \| N-(4-chloroph...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	n/a	2.40E+3	n/a	n/a	n/a	n/a	n/a
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Vascular endothelial growth factor receptor 2 (Human)	BDBM4851 (cid_151194 \| PTK787 \| CHEMBL101253 \| N-(4-chloroph...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	54	n/a	n/a	n/a	n/a	n/a	25
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Vascular endothelial growth factor receptor 1 (Human)	BDBM4851 (cid_151194 \| PTK787 \| CHEMBL101253 \| N-(4-chloroph...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	140	n/a	n/a	n/a	n/a	7.5	25
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Bile salt export pump (Human)	BDBM4851 (cid_151194 \| PTK787 \| CHEMBL101253 \| N-(4-chloroph...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	<1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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HLA class I histocompatibility antigen, A alpha chain (Human)	BDBM4851 (cid_151194 \| PTK787 \| CHEMBL101253 \| N-(4-chloroph...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	n/a	2.12E+4	n/a	n/a	n/a	n/a	n/a
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Vascular endothelial growth factor receptor 2 (Human)	BDBM4851 (cid_151194 \| PTK787 \| CHEMBL101253 \| N-(4-chloroph...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	43	n/a	n/a	n/a	n/a	n/a	n/a
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Vascular endothelial growth factor receptor 2 (Human)	BDBM4851 (cid_151194 \| PTK787 \| CHEMBL101253 \| N-(4-chloroph...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	180	n/a	n/a	n/a	n/a	n/a	n/a
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Vascular endothelial growth factor receptor 2 (Human)	BDBM4851 (cid_151194 \| PTK787 \| CHEMBL101253 \| N-(4-chloroph...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
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Vascular endothelial growth factor receptor 1 (Human)	BDBM4851 (cid_151194 \| PTK787 \| CHEMBL101253 \| N-(4-chloroph...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
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Cyclin-dependent kinase 1 (Human)	BDBM4851 (cid_151194 \| PTK787 \| CHEMBL101253 \| N-(4-chloroph...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Proto-oncogene tyrosine-protein kinase Src (Human)	BDBM4851 (cid_151194 \| PTK787 \| CHEMBL101253 \| N-(4-chloroph...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Epidermal growth factor receptor (Human)	BDBM4851 (cid_151194 \| PTK787 \| CHEMBL101253 \| N-(4-chloroph...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Insulin-like growth factor 1 receptor (Human)	BDBM4851 (cid_151194 \| PTK787 \| CHEMBL101253 \| N-(4-chloroph...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Vascular endothelial growth factor receptor 2 (Human)	BDBM4851 (cid_151194 \| PTK787 \| CHEMBL101253 \| N-(4-chloroph...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	37	n/a	n/a	n/a	n/a	n/a	n/a
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Mast/stem cell growth factor receptor Kit (Human)	BDBM4851 (cid_151194 \| PTK787 \| CHEMBL101253 \| N-(4-chloroph...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	730	n/a	n/a	n/a	n/a	n/a	n/a
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Hepatocyte growth factor receptor (Human)	BDBM4851 (cid_151194 \| PTK787 \| CHEMBL101253 \| N-(4-chloroph...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Vascular endothelial growth factor receptor 1 (Human)	BDBM4851 (cid_151194 \| PTK787 \| CHEMBL101253 \| N-(4-chloroph...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	77	n/a	n/a	n/a	n/a	n/a	n/a
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cAMP-dependent protein kinase catalytic subunit alpha/beta/gamma (Human)	BDBM4851 (cid_151194 \| PTK787 \| CHEMBL101253 \| N-(4-chloroph...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Vascular endothelial growth factor receptor 3 (Human)	BDBM4851 (cid_151194 \| PTK787 \| CHEMBL101253 \| N-(4-chloroph...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	n/a	190	n/a	n/a	n/a	n/a	n/a
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Protein-tyrosine kinase 6 (Human)	BDBM4851 (cid_151194 \| PTK787 \| CHEMBL101253 \| N-(4-chloroph...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	n/a	2.70E+3	n/a	n/a	n/a	n/a	n/a
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Vascular endothelial growth factor receptor 2 (Human)	BDBM4851 (cid_151194 \| PTK787 \| CHEMBL101253 \| N-(4-chloroph...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	n/a	70	n/a	n/a	n/a	n/a	n/a
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Platelet-derived growth factor receptor beta (Human)	BDBM4851 (cid_151194 \| PTK787 \| CHEMBL101253 \| N-(4-chloroph...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	n/a	58	n/a	n/a	n/a	n/a	n/a
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Mast/stem cell growth factor receptor Kit (Human)	BDBM4851 (cid_151194 \| PTK787 \| CHEMBL101253 \| N-(4-chloroph...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	n/a	700	n/a	n/a	n/a	n/a	n/a
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Vascular endothelial growth factor receptor 2 (Human)	BDBM4851 (cid_151194 \| PTK787 \| CHEMBL101253 \| N-(4-chloroph...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	63	n/a	n/a	n/a	n/a	n/a	n/a
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Vascular endothelial growth factor receptor 2 (Human)	BDBM4851 (cid_151194 \| PTK787 \| CHEMBL101253 \| N-(4-chloroph...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	<15	n/a	n/a	n/a	n/a	n/a	n/a
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Vascular endothelial growth factor receptor 2 (Human)	BDBM4851 (cid_151194 \| PTK787 \| CHEMBL101253 \| N-(4-chloroph...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	138	n/a	n/a	n/a	n/a	n/a	n/a
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Vascular endothelial growth factor receptor 2 (Human)	BDBM4851 (cid_151194 \| PTK787 \| CHEMBL101253 \| N-(4-chloroph...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	138	n/a	n/a	n/a	n/a	n/a	n/a
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Vascular endothelial growth factor receptor 1 (Human)	BDBM4851 (cid_151194 \| PTK787 \| CHEMBL101253 \| N-(4-chloroph...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	140	n/a	n/a	n/a	n/a	n/a	n/a
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Vascular endothelial growth factor receptor 2 (Human)	BDBM4851 (cid_151194 \| PTK787 \| CHEMBL101253 \| N-(4-chloroph...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	54	n/a	n/a	n/a	n/a	n/a	n/a
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Vascular endothelial growth factor receptor 2 (Human)	BDBM4851 (cid_151194 \| PTK787 \| CHEMBL101253 \| N-(4-chloroph...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	21	n/a	n/a	n/a	n/a	n/a	n/a
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Vascular endothelial growth factor receptor 2 (Human)	BDBM4851 (cid_151194 \| PTK787 \| CHEMBL101253 \| N-(4-chloroph...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	54	n/a	n/a	n/a	n/a	n/a	n/a
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Vascular endothelial growth factor receptor 1 (Human)	BDBM4851 (cid_151194 \| PTK787 \| CHEMBL101253 \| N-(4-chloroph...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	140	n/a	n/a	n/a	n/a	n/a	n/a
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Vascular endothelial growth factor receptor 3 (Human)	BDBM4851 (cid_151194 \| PTK787 \| CHEMBL101253 \| N-(4-chloroph...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	64	n/a	n/a	n/a	n/a	n/a	n/a
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Vascular endothelial growth factor receptor 1 (Human)	BDBM4851 (cid_151194 \| PTK787 \| CHEMBL101253 \| N-(4-chloroph...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	77	n/a	n/a	n/a	n/a	n/a	n/a
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Vascular endothelial growth factor receptor 2 (Mouse)	BDBM4851 (cid_151194 \| PTK787 \| CHEMBL101253 \| N-(4-chloroph...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	270	n/a	n/a	n/a	n/a	n/a	n/a
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Vascular endothelial growth factor receptor 2 (Human)	BDBM4851 (cid_151194 \| PTK787 \| CHEMBL101253 \| N-(4-chloroph...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	34	n/a	n/a	n/a	n/a	n/a	n/a
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