BDBM486 (2S)-N-[(2S,3R)-4-[(tert-butylcarbamoyl)(3-methylbutyl)amino]-3-hydroxy-1-phenylbutan-2-yl]-2-(quinolin-2-ylformamido)butanediamide::(Hydroxyethyl)urea Isostere deriv. 14

SMILES CC(C)CCN(C[C@@H](O)[C@H](Cc1ccccc1)NC(=O)[C@H](CC(N)=O)NC(=O)c1ccc2ccccc2n1)C(=O)NC(C)(C)C

InChI Key InChIKey=OOOXXPKYELPWCH-YTCPBCGMSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 486   

TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Washington University

Curated by ChEMBL
LigandPNGBDBM486((2S)-N-[(2S,3R)-4-[(tert-butylcarbamoyl)(3-methylb...)
Affinity DataIC50:  3nMAssay Description:Inhibitory activity against HIV-1 ProteaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Monsanto Corporate Research

LigandPNGBDBM486((2S)-N-[(2S,3R)-4-[(tert-butylcarbamoyl)(3-methylb...)
Affinity DataIC50:  3nMpH: 6.4 T: 2°CAssay Description:IC50 values for inhibition of recombinant HIV protease were determined using the spectrofluorometric assay, which utilized an intramolecularly quench...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed