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BDBM48663 (4E)-4-[(4-fluorophenyl)hydrazinylidene]-2-phenyl-5-(pyridin-2-ylsulfanylmethyl)pyrazol-3-one::(4E)-4-[(4-fluorophenyl)hydrazinylidene]-2-phenyl-5-[(2-pyridinylthio)methyl]-3-pyrazolone::(4E)-4-[(4-fluorophenyl)hydrazono]-2-phenyl-5-[(2-pyridylthio)methyl]-2-pyrazolin-3-one::4-[(4-Fluoro-phenyl)-hydrazono]-2-phenyl-5-(pyridin-2-ylsulfanylmethyl)-2,4-dihydro-pyrazol-3-one::MLS000550955::SMR000145083::cid_7360902

SMILES: Fc1ccc(cc1)N=Nc1c(CSc2ccccn2)[nH]n(-c2ccccc2)c1=O

InChI Key: InChIKey=KYBJGQYWWLRQGZ-OCOZRVBESA-N

Data: 2 IC50

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   Substructure
Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 48663   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
neutrophil cytosolic factor 1


(Homo sapiens (Human))
BDBM48663
PNG
((4E)-4-[(4-fluorophenyl)hydrazinylidene]-2-phenyl-...)
Show SMILES Fc1ccc(cc1)N=Nc1c(CSc2ccccn2)[nH]n(-c2ccccc2)c1=O
Show InChI InChI=1S/C21H16FN5OS/c22-15-9-11-16(12-10-15)24-25-20-18(14-29-19-8-4-5-13-23-19)26-27(21(20)28)17-6-2-1-3-7-17/h1-13,26H,14H2/b25-24+
PDB
MMDB

Reactome pathway
KEGG

B.MOAD
DrugBank
GoogleScholar
PC cid
PC sid
UniChem
PCBioAssay
n/an/a 5.00E+4n/an/an/an/an/an/a



Emory University

Curated by PubChem BioAssay


Assay Description
NIH Molecular Libraries Screening Centers Network [MLSCN] Emory Chemical Biology Discovery Center in MLSCN Assay provider: Susan Smith, Emory Univers...


PubChem Bioassay (2008)


BindingDB Entry DOI: 10.7270/Q2M90723
More data for this
Ligand-Target Pair
eukaryotic translation initiation factor 4 gamma, 1 isoform 4


(Homo sapiens (Human))
BDBM48663
PNG
((4E)-4-[(4-fluorophenyl)hydrazinylidene]-2-phenyl-...)
Show SMILES Fc1ccc(cc1)N=Nc1c(CSc2ccccn2)[nH]n(-c2ccccc2)c1=O
Show InChI InChI=1S/C21H16FN5OS/c22-15-9-11-16(12-10-15)24-25-20-18(14-29-19-8-4-5-13-23-19)26-27(21(20)28)17-6-2-1-3-7-17/h1-13,26H,14H2/b25-24+
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
PCBioAssay
n/an/a 6.40E+4n/an/an/an/an/an/a



Emory University

Curated by PubChem BioAssay


Assay Description
Dose Response Confirmation for Small Molecule Inhibitors of Eukaryotic Translation Initiation NIH Molecular Libraries Screening Centers Network [MLSC...


PubChem Bioassay (2009)


BindingDB Entry DOI: 10.7270/Q2RN3686
More data for this
Ligand-Target Pair