BDBM4882 (Z)-3-[(3-(2-Carboxyethyl)-4-methylpyrrol-2-yl)methylidenyl]indolin-2-one::3-(4-methyl-2-{[(3Z)-2-oxo-2,3-dihydro-1H-indol-3-ylidene]methyl}-1H-pyrrol-3-yl)propanoic acid::CHEMBL89363::KDR Kinase Inhibitor, 5::SU5402

SMILES: Cc1c[nH]c(\C=C2/C(=O)Nc3ccccc23)c1CCC(O)=O

InChI Key: InChIKey=JNDVEAXZWJIOKB-UHFFFAOYSA-N

Data: 21 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 21 hits for monomerid = 4882   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Insulin-like growth factor 1 receptor (Human)	BDBM4882 (3-(4-methyl-2-{[(3Z)-2-oxo-2,3-dihydro-1H-indol-3-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Fibroblast growth factor receptor 1 (Mouse)	BDBM4882 (3-(4-methyl-2-{[(3Z)-2-oxo-2,3-dihydro-1H-indol-3-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 1 (Human)	BDBM4882 (3-(4-methyl-2-{[(3Z)-2-oxo-2,3-dihydro-1H-indol-3-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Vascular endothelial growth factor receptor 2 (Human)	BDBM4882 (3-(4-methyl-2-{[(3Z)-2-oxo-2,3-dihydro-1H-indol-3-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 1 (Human)	BDBM4882 (3-(4-methyl-2-{[(3Z)-2-oxo-2,3-dihydro-1H-indol-3-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	334	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 1 (Mouse)	BDBM4882 (3-(4-methyl-2-{[(3Z)-2-oxo-2,3-dihydro-1H-indol-3-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 1 (Human)	BDBM4882 (3-(4-methyl-2-{[(3Z)-2-oxo-2,3-dihydro-1H-indol-3-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Epidermal growth factor receptor (Human)	BDBM4882 (3-(4-methyl-2-{[(3Z)-2-oxo-2,3-dihydro-1H-indol-3-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
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Platelet-derived growth factor receptor beta (Human)	BDBM4882 (3-(4-methyl-2-{[(3Z)-2-oxo-2,3-dihydro-1H-indol-3-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	6.09E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 1 (Mouse)	BDBM4882 (3-(4-methyl-2-{[(3Z)-2-oxo-2,3-dihydro-1H-indol-3-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	400	n/a	n/a	n/a	n/a	n/a	n/a
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Receptor tyrosine-protein kinase erbB-2 (Human)	BDBM4882 (3-(4-methyl-2-{[(3Z)-2-oxo-2,3-dihydro-1H-indol-3-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Human)	BDBM4882 (3-(4-methyl-2-{[(3Z)-2-oxo-2,3-dihydro-1H-indol-3-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	20	n/a	n/a	n/a	n/a	7.5	22
TBA									Citation and Details
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Human)	BDBM4882 (3-(4-methyl-2-{[(3Z)-2-oxo-2,3-dihydro-1H-indol-3-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Human)	BDBM4882 (3-(4-methyl-2-{[(3Z)-2-oxo-2,3-dihydro-1H-indol-3-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Human)	BDBM4882 (3-(4-methyl-2-{[(3Z)-2-oxo-2,3-dihydro-1H-indol-3-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	510	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase Src (Human)	BDBM4882 (3-(4-methyl-2-{[(3Z)-2-oxo-2,3-dihydro-1H-indol-3-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.06E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 1 (Human)	BDBM4882 (3-(4-methyl-2-{[(3Z)-2-oxo-2,3-dihydro-1H-indol-3-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	30	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Human)	BDBM4882 (3-(4-methyl-2-{[(3Z)-2-oxo-2,3-dihydro-1H-indol-3-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	20	n/a	n/a	n/a	n/a	7.5	22
TBA									Citation and Details
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Human)	BDBM4882 (3-(4-methyl-2-{[(3Z)-2-oxo-2,3-dihydro-1H-indol-3-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Human)	BDBM4882 (3-(4-methyl-2-{[(3Z)-2-oxo-2,3-dihydro-1H-indol-3-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	510	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 1 (Human)	BDBM4882 (3-(4-methyl-2-{[(3Z)-2-oxo-2,3-dihydro-1H-indol-3-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	30	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair