BDBM4883 3-(4-methyl-2-{[(3Z)-4-methyl-2-oxo-2,3-dihydro-1H-indol-3-ylidene]methyl}-1H-pyrrol-3-yl)propanoic acid::3-substituted indolin-2-one 9a::SU5402 analog 9a

SMILES: Cc1c[nH]c(\C=C2/C(=O)Nc3cccc(C)c23)c1CCC(O)=O

InChI Key: InChIKey=WFEYKXAXXWJCGD-UHFFFAOYSA-N

Data: 4 IC50

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Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 4883   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Vascular endothelial growth factor receptor 2 (Human)	BDBM4883 (SU5402 analog 9a | 3-(4-methyl-2-{[(3Z)-4-methyl-2...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	200	n/a	n/a	n/a	n/a	7.5	22
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Fibroblast growth factor receptor 1 (Human)	BDBM4883 (SU5402 analog 9a | 3-(4-methyl-2-{[(3Z)-4-methyl-2...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	30	n/a	n/a	n/a	n/a	n/a	n/a
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Platelet-derived growth factor receptor beta (Human)	BDBM4883 (SU5402 analog 9a | 3-(4-methyl-2-{[(3Z)-4-methyl-2...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.11E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Epidermal growth factor receptor (Human)	BDBM4883 (SU5402 analog 9a | 3-(4-methyl-2-{[(3Z)-4-methyl-2...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
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