BDBM4886 3-(2-{[(3Z)-6-(3-ethoxyphenyl)-2-oxo-2,3-dihydro-1H-indol-3-ylidene]methyl}-4-methyl-1H-pyrrol-3-yl)propanoic acid::3-substituted indolin-2-one 9d::SU5402 analog 9d
SMILES CCOc1cccc(c1)-c1ccc2\C(=C\c3[nH]cc(C)c3CCC(O)=O)C(=O)Nc2c1
InChI Key InChIKey=OYFXUFAPLNTDRA-BKUYFWCQSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 4886
Affinity DataIC50: 1.00E+3nMpH: 7.5 T: 2°CAssay Description:The assays were performed in 96-well microtiter plates that had been coated with a polyGluTyr peptide. Negative control wells received buffer alone w...More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+5nMAssay Description:IC50 is the inhibitor concentration which inhibits 50% of EGF-R or PDGFR-beta kinase autophosphorylation activity. The assay was performed in 96-well...More data for this Ligand-Target Pair
Affinity DataIC50: 2.38E+3nMAssay Description:IC50 is the inhibitor concentration which inhibits 50% of EGF-R or PDGFR-beta kinase autophosphorylation activity. The assay was performed in 96-well...More data for this Ligand-Target Pair
Affinity DataIC50: 4.50E+3nMAssay Description:The assays were performed in 96-well microtiter plates that had been coated with a polyGluTyr peptide. Negative control wells received buffer alone w...More data for this Ligand-Target Pair