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BDBM4892 3-(5-{[(3Z)-6-(3-methoxyphenyl)-2-oxo-2,3-dihydro-1H-indol-3-ylidene]methyl}-4-methyl-1H-pyrrol-3-yl)propanoic acid::3-substituted indolin-2-one 11f::3-{5-[6-(3-Methoxy-phenyl)-2-oxo-1,2-dihydroindol-3-ylidenemethyl]-4-methyl-1H-pyrrol-3-yl}propionic Acid::SU5402 analog 11f
SMILES: COc1cccc(c1)-c1ccc2\C(=C\c3[nH]cc(CCC(O)=O)c3C)C(=O)Nc2c1
InChI Key: InChIKey=YAHVZVQVATYZMK-UHFFFAOYSA-N
Data: 4 IC50
| Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Vascular endothelial growth factor receptor 2 (Human) | BDBM4892![]() (3-{5-[6-(3-Methoxy-phenyl)-2-oxo-1,2-dihydroindol-...) | GoogleScholar | UniChem | n/a | n/a | 90 | n/a | n/a | n/a | n/a | 7.5 | 22 | |
TBA | Citation and Details | ||||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Fibroblast growth factor receptor 1 (Human) | BDBM4892![]() (3-{5-[6-(3-Methoxy-phenyl)-2-oxo-1,2-dihydroindol-...) | GoogleScholar | UniChem | n/a | n/a | 360 | n/a | n/a | n/a | n/a | n/a | n/a | |
TBA | Citation and Details | ||||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Platelet-derived growth factor receptor beta (Human) | BDBM4892![]() (3-{5-[6-(3-Methoxy-phenyl)-2-oxo-1,2-dihydroindol-...) | GoogleScholar | UniChem | n/a | n/a | 170 | n/a | n/a | n/a | n/a | n/a | n/a | |
TBA | Citation and Details | ||||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Epidermal growth factor receptor (Human) | BDBM4892![]() (3-{5-[6-(3-Methoxy-phenyl)-2-oxo-1,2-dihydroindol-...) | GoogleScholar | UniChem | n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a | |
TBA | Citation and Details | ||||||||||||
| More data for this Ligand-Target Pair | |||||||||||||