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BDBM4900 3-(2,4-dimethyl-5-{[(3Z)-2-oxo-6-phenyl-2,3-dihydro-1H-indol-3-ylidene]methyl}-1H-pyrrol-3-yl)propanoic acid::3-substituted indolin-2-one 16f::CHEMBL149201
SMILES: Cc1[nH]c(\C=C2/C(=O)Nc3cc(ccc23)-c2ccccc2)c(C)c1CCC(O)=O
InChI Key: InChIKey=APYYTEJNOZQZNA-UHFFFAOYSA-N
Data: 5 IC50
| Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Vascular endothelial growth factor receptor 2 (Human) | BDBM4900![]() (CHEMBL149201 | 3-(2,4-dimethyl-5-{[(3Z)-2-oxo-6-ph...) | GoogleScholar | UniChem | n/a | n/a | 140 | n/a | n/a | n/a | n/a | n/a | n/a | |
TBA | Citation and Details | ||||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Fibroblast growth factor receptor 1 (Human) | BDBM4900![]() (CHEMBL149201 | 3-(2,4-dimethyl-5-{[(3Z)-2-oxo-6-ph...) | GoogleScholar | UniChem | n/a | n/a | 2.29E+3 | n/a | n/a | n/a | n/a | n/a | n/a | |
TBA | Citation and Details | ||||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Platelet-derived growth factor receptor beta (Human) | BDBM4900![]() (CHEMBL149201 | 3-(2,4-dimethyl-5-{[(3Z)-2-oxo-6-ph...) | GoogleScholar | UniChem | n/a | n/a | 10 | n/a | n/a | n/a | n/a | n/a | n/a | |
TBA | Citation and Details | ||||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Epidermal growth factor receptor (Human) | BDBM4900![]() (CHEMBL149201 | 3-(2,4-dimethyl-5-{[(3Z)-2-oxo-6-ph...) | GoogleScholar | UniChem | n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a | |
TBA | Citation and Details | ||||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Fibroblast growth factor receptor 1 (Human) | BDBM4900![]() (CHEMBL149201 | 3-(2,4-dimethyl-5-{[(3Z)-2-oxo-6-ph...) | GoogleScholar | UniChem | n/a | n/a | >5.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | |
TBA | Citation and Details | ||||||||||||
| More data for this Ligand-Target Pair | |||||||||||||