BindingDB logo
myBDB logout

BDBM49021 (1-benzylbenzimidazol-2-yl)-(2-furfuryl)amine::1-benzyl-N-(furan-2-ylmethyl)benzimidazol-2-amine::MLS000084083::N-(2-furanylmethyl)-1-(phenylmethyl)-2-benzimidazolamine::N-(furan-2-ylmethyl)-1-(phenylmethyl)benzimidazol-2-amine::SMR000048469::cid_667146

SMILES: C(Nc1nc2ccccc2n1Cc1ccccc1)c1ccco1

InChI Key: InChIKey=OECUWHDVQIITIS-UHFFFAOYSA-N

Data: 1 IC50  1 EC50

Find this compound or compounds like it in BindingDB:
Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 49021   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Short transient receptor potential channel 5


(Mus musculus)
BDBM49021
PNG
((1-benzylbenzimidazol-2-yl)-(2-furfuryl)amine | 1-...)
Show SMILES C(Nc1nc2ccccc2n1Cc1ccccc1)c1ccco1
Show InChI InChI=1S/C19H17N3O/c1-2-7-15(8-3-1)14-22-18-11-5-4-10-17(18)21-19(22)20-13-16-9-6-12-23-16/h1-12H,13-14H2,(H,20,21)
PDB
MMDB

UniProtKB/SwissProt
UniProtKB/TrEMBL

DrugBank
GoogleScholar
Purchase

PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 4.06E+3n/an/an/an/an/an/a



University of Nebraska Medical Center

Curated by ChEMBL


Assay Description
Inhibition of mouse TRPC5 expressed in Flp-In-T-Rex-HEK293 cells assessed as reduction in rulizole-induced channel current by automated patch clamp m...


Bioorg Med Chem Lett 29: 155-159 (2019)


Article DOI: 10.1016/j.bmcl.2018.12.007
More data for this
Ligand-Target Pair
D(1A) dopamine receptor


(Homo sapiens (Human))
BDBM49021
PNG
((1-benzylbenzimidazol-2-yl)-(2-furfuryl)amine | 1-...)
Show SMILES C(Nc1nc2ccccc2n1Cc1ccccc1)c1ccco1
Show InChI InChI=1S/C19H17N3O/c1-2-7-15(8-3-1)14-22-18-11-5-4-10-17(18)21-19(22)20-13-16-9-6-12-23-16/h1-12H,13-14H2,(H,20,21)
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
Purchase

PC cid
PC sid
UniChem

Similars

PCBioAssay
n/an/an/an/a 0.00350n/an/an/an/a



Vanderbilt Screening Center for GPCRs, Ion Channels and Transporters

Curated by PubChem BioAssay


Assay Description
Assay Provider: Val Watts Assay Provider Affiliation: Purdue University Grant Title: Allosteric Modulators of D1 Receptors Grant Number: 1 X01 MH0776...


PubChem Bioassay (2007)


BindingDB Entry DOI: 10.7270/Q2H41PVH
More data for this
Ligand-Target Pair