BDBM4911 (3Z)-6-(2-methoxyphenyl)-3-(4,5,6,7-tetrahydro-1H-indol-2-ylmethylidene)-2,3-dihydro-1H-indol-2-one::6-(2-Methoxyphenyl)-3-(4,5,6,7-tetrahydro-1H-indol-2-ylmethylene)-1,3-dihydroindol-2-one::Indolin-2-one deriv. 4h

SMILES COc1ccccc1-c1ccc2\C(=C\c3cc4CCCCc4[nH]3)C(=O)Nc2c1

InChI Key InChIKey=PFORQVNUDXKNNV-ZHZULCJRSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 4911   

TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Sugen

LigandPNGBDBM4911((3Z)-6-(2-methoxyphenyl)-3-(4,5,6,7-tetrahydro-1H-...)
Affinity DataIC50:  2.00E+4nMpH: 7.5 T: 2°CAssay Description:The assays were performed in 96-well microtiter plates that had been coated with a polyGluTyr peptide. Negative control wells received buffer alone w...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Sugen

LigandPNGBDBM4911((3Z)-6-(2-methoxyphenyl)-3-(4,5,6,7-tetrahydro-1H-...)
Affinity DataIC50:  1.77E+4nMAssay Description:The assays were performed in 96-well microtiter plates that had been coated with a polyGluTyr peptide. Negative control wells received buffer alone w...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Sugen

LigandPNGBDBM4911((3Z)-6-(2-methoxyphenyl)-3-(4,5,6,7-tetrahydro-1H-...)
Affinity DataIC50: >1.00E+5nMAssay Description:IC50 is the inhibitor concentration which inhibits 50% of EGF-R or PDGFR-beta kinase autophosphorylation activity. The assay was performed in 96-well...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
Sugen

LigandPNGBDBM4911((3Z)-6-(2-methoxyphenyl)-3-(4,5,6,7-tetrahydro-1H-...)
Affinity DataIC50:  1.39E+4nMAssay Description:IC50 is the inhibitor concentration which inhibits 50% of EGF-R or PDGFR-beta kinase autophosphorylation activity. The assay was performed in 96-well...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Sugen

LigandPNGBDBM4911((3Z)-6-(2-methoxyphenyl)-3-(4,5,6,7-tetrahydro-1H-...)
Affinity DataIC50: >2.00E+4nMAssay Description:The assays were performed in 96-well microtiter plates that had been coated with a polyGluTyr peptide. Negative control wells received buffer alone w...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed