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BDBM4919 3-(2-{[(3Z)-2-oxo-6-phenyl-2,3-dihydro-1H-indol-3-ylidene]methyl}-4,5,6,7-tetrahydro-1H-indol-3-yl)propanoic acid::3-[2-(2-Oxo-6-phenyl-1,2-dihydroindol-3-ylidenemethyl)-4,5,6,7-tetrahydro-1H-indol-3-yl]propionic Acid::Indolin-2-one deriv. 9f
SMILES: OC(=O)CCc1c(\C=C2/C(=O)Nc3cc(ccc23)-c2ccccc2)[nH]c2CCCCc12
InChI Key: InChIKey=NQIZOXPPUYQOQV-UHFFFAOYSA-N
Data: 5 IC50
| Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Vascular endothelial growth factor receptor 2 (Human) | BDBM4919![]() (3-(2-{[(3Z)-2-oxo-6-phenyl-2,3-dihydro-1H-indol-3-...) | GoogleScholar | UniChem | n/a | n/a | 50 | n/a | n/a | n/a | n/a | 7.5 | 22 | |
TBA | Citation and Details | ||||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Fibroblast growth factor receptor 1 (Human) | BDBM4919![]() (3-(2-{[(3Z)-2-oxo-6-phenyl-2,3-dihydro-1H-indol-3-...) | GoogleScholar | UniChem | n/a | n/a | 1.27E+3 | n/a | n/a | n/a | n/a | n/a | n/a | |
TBA | Citation and Details | ||||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Proto-oncogene tyrosine-protein kinase Src (Human) | BDBM4919![]() (3-(2-{[(3Z)-2-oxo-6-phenyl-2,3-dihydro-1H-indol-3-...) | GoogleScholar | UniChem | n/a | n/a | 110 | n/a | n/a | n/a | n/a | n/a | n/a | |
TBA | Citation and Details | ||||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Platelet-derived growth factor receptor beta (Human) | BDBM4919![]() (3-(2-{[(3Z)-2-oxo-6-phenyl-2,3-dihydro-1H-indol-3-...) | GoogleScholar | UniChem | n/a | n/a | 40 | n/a | n/a | n/a | n/a | n/a | n/a | |
TBA | Citation and Details | ||||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Epidermal growth factor receptor (Human) | BDBM4919![]() (3-(2-{[(3Z)-2-oxo-6-phenyl-2,3-dihydro-1H-indol-3-...) | GoogleScholar | UniChem | n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a | |
TBA | Citation and Details | ||||||||||||
| More data for this Ligand-Target Pair | |||||||||||||