BDBM492 (Hydroxyethyl)urea Isostere deriv. 20::benzyl N-[(1S)-1-{[(2S,3R)-4-[(tert-butylcarbamoyl)[(1S)-1-phenylethyl]amino]-3-hydroxy-1-phenylbutan-2-yl]carbamoyl}-2-carbamoylethyl]carbamate
SMILES C[C@H](N(C[C@@H](O)[C@H](Cc1ccccc1)NC(=O)[C@H](CC(N)=O)NC(=O)OCc1ccccc1)C(=O)NC(C)(C)C)c1ccccc1
InChI Key InChIKey=JWZDCFNILWOTAP-DNEFNOKRSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 492
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Monsanto Corporate Research
Monsanto Corporate Research
Affinity DataIC50: 5.10E+3nMpH: 6.4 T: 2°CAssay Description:IC50 values for inhibition of recombinant HIV protease were determined using the spectrofluorometric assay, which utilized an intramolecularly quench...More data for this Ligand-Target Pair