BDBM4920 3-(2-{[(3Z)-6-(3-methoxyphenyl)-2-oxo-2,3-dihydro-1H-indol-3-ylidene]methyl}-4,5,6,7-tetrahydro-1H-indol-3-yl)propanoic acid::3-{2-[6-(3-Methoxyphenyl)-2-oxo-1,2-dihydroindol-3ylidenemethyl]-4,5,6,7-tetrahydro-1H-indol-3-yl}-propionic Acid::Indolin-2-one deriv. 9g

SMILES COc1cccc(c1)-c1ccc2\C(=C\c3[nH]c4CCCCc4c3CCC(O)=O)C(=O)Nc2c1

InChI Key InChIKey=FUXHNAHZJZOIIP-JCMHNJIXSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 4920   

TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Sugen

LigandPNGBDBM4920(3-(2-{[(3Z)-6-(3-methoxyphenyl)-2-oxo-2,3-dihydro-...)
Affinity DataIC50:  70nMpH: 7.5 T: 2°CAssay Description:The assays were performed in 96-well microtiter plates that had been coated with a polyGluTyr peptide. Negative control wells received buffer alone w...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Sugen

LigandPNGBDBM4920(3-(2-{[(3Z)-6-(3-methoxyphenyl)-2-oxo-2,3-dihydro-...)
Affinity DataIC50:  1.35E+3nMAssay Description:The assays were performed in 96-well microtiter plates that had been coated with a polyGluTyr peptide. Negative control wells received buffer alone w...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Sugen

LigandPNGBDBM4920(3-(2-{[(3Z)-6-(3-methoxyphenyl)-2-oxo-2,3-dihydro-...)
Affinity DataIC50:  8.88E+3nMAssay Description:IC50 is the inhibitor concentration which inhibits 50% of EGF-R or PDGFR-beta kinase autophosphorylation activity. The assay was performed in 96-well...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
Sugen

LigandPNGBDBM4920(3-(2-{[(3Z)-6-(3-methoxyphenyl)-2-oxo-2,3-dihydro-...)
Affinity DataIC50:  680nMAssay Description:IC50 is the inhibitor concentration which inhibits 50% of EGF-R or PDGFR-beta kinase autophosphorylation activity. The assay was performed in 96-well...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Sugen

LigandPNGBDBM4920(3-(2-{[(3Z)-6-(3-methoxyphenyl)-2-oxo-2,3-dihydro-...)
Affinity DataIC50:  100nMAssay Description:The assays were performed in 96-well microtiter plates that had been coated with a polyGluTyr peptide. Negative control wells received buffer alone w...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed