BDBM496597 CVD-0005378::MAT-POS-590ac91e-32::acs.jmedchem.1c00409_ST.394

SMILES COc1ccccc1OCCNC(=O)C2=CC(=O)Nc3c2ccc(c3)F

InChI Key InChIKey=KKIJAAYVRSUCNW-UHFFFAOYSA-N

Data  1 KI  4 IC50

PDB links: 1 PDB ID matches this monomer.

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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 496597   

TargetReplicase polyprotein 1ab(2019-nCoV)
Michigan State University

LigandPNGBDBM496597(MAT-POS-590ac91e-32 | acs.jmedchem.1c00409_ST.394 ...)
Affinity DataKi:  8.65E+3nMAssay Description:This is a review article. Please point to the original journal.More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/27/2022
Entry Details Article
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Michigan State University

LigandPNGBDBM496597(MAT-POS-590ac91e-32 | acs.jmedchem.1c00409_ST.394 ...)
Affinity DataIC50: 1.82E+4nMAssay Description:This is a review article. Please point to the original journal.More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/27/2022
Entry Details Article
PubMed
TargetSerine protease 1(Human)
Israel Institution of Biological Research

LigandPNGBDBM496597(MAT-POS-590ac91e-32 | acs.jmedchem.1c00409_ST.394 ...)
Affinity DataIC50: 9.90E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/5/2021
Entry Details Article

TargetReplicase polyprotein 1ab(2019-nCoV)
Michigan State University

LigandPNGBDBM496597(MAT-POS-590ac91e-32 | acs.jmedchem.1c00409_ST.394 ...)
Affinity DataIC50: 9.95E+4nMAssay Description:Compounds were seeded into assay-ready plates (Greiner 384 low volume, cat. no. 784900) using an Echo 555 acoustic dispenser, and dimethyl sulfoxide ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2023
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Michigan State University

LigandPNGBDBM496597(MAT-POS-590ac91e-32 | acs.jmedchem.1c00409_ST.394 ...)
Affinity DataIC50: 9.95E+4nMAssay Description:Compounds were seeded into assay-ready plates (Greiner 384 low volume, cat 784900) using an Echo 555 acoustic dispenser, and DMSO was back-filled for...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/5/2021
Entry Details Article