BDBM496783 CVD-0003624::TRY-UNI-714a760b-20

SMILES Cc1ccncc1NC(=O)Cc2cccc(c2)C#N

InChI Key InChIKey=OTFRLGRHXMKEAF-UHFFFAOYSA-N

Data  4 IC50

PDB links: 1 PDB ID matches this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 496783   

TargetReplicase polyprotein 1ab(2019-nCoV)
Israel Institution of Biological Research

LigandPNGBDBM496783(TRY-UNI-714a760b-20 | CVD-0003624)
Affinity DataIC50: 4.38E+4nMAssay Description:The assay was performed according to the published procedure. Briefly, compounds were seeded into assay-ready plates (Greiner 384PP, cat# 781280) usi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/5/2021
Entry Details Article

TargetReplicase polyprotein 1ab(2019-nCoV)
Israel Institution of Biological Research

LigandPNGBDBM496783(TRY-UNI-714a760b-20 | CVD-0003624)
Affinity DataIC50: 6.13E+4nMAssay Description:Compounds were seeded into assay-ready plates (Greiner 384 low volume, cat 784900) using an Echo 555 acoustic dispenser, and DMSO was back-filled for...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/5/2021
Entry Details Article

TargetReplicase polyprotein 1ab(2019-nCoV)
Israel Institution of Biological Research

LigandPNGBDBM496783(TRY-UNI-714a760b-20 | CVD-0003624)
Affinity DataIC50: 6.14E+4nMAssay Description:Compounds were seeded into assay-ready plates (Greiner 384 low volume, cat. no. 784900) using an Echo 555 acoustic dispenser, and dimethyl sulfoxide ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2023
Entry Details
PubMed
TargetSerine protease 1(Human)
Israel Institution of Biological Research

LigandPNGBDBM496783(TRY-UNI-714a760b-20 | CVD-0003624)
Affinity DataIC50: 9.90E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/5/2021
Entry Details Article