BDBM497 (Hydroxyethyl)urea Isostere deriv. 25::benzyl N-[(1S)-2-carbamoyl-1-{[(2S,3S)-3-hydroxy-4-[(methylcarbamoyl)(2-methylpropyl)amino]-1-phenylbutan-2-yl]carbamoyl}ethyl]carbamate
SMILES CNC(=O)N(CC(C)C)C[C@H](O)[C@H](Cc1ccccc1)NC(=O)[C@H](CC(N)=O)NC(=O)OCc1ccccc1
InChI Key InChIKey=KGHZDRBKSVQHQS-HJOGWXRNSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 497
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Monsanto Corporate Research
Monsanto Corporate Research
Affinity DataIC50: >1.00E+4nMpH: 6.4 T: 2°CAssay Description:IC50 values for inhibition of recombinant HIV protease were determined using the spectrofluorometric assay, which utilized an intramolecularly quench...More data for this Ligand-Target Pair