BDBM50000306 6-Pyridin-3-yl-3,4-dihydro-1H-quinolin-2-one::6-Pyridin-3-yl-3,4-dihydro-1H-quinolin-2-one; HCL::6-Pyridin-3-yl-3,4-dihydroquinolin-2(1H)-on::CHEMBL62811

SMILES: O=C1CCc2cc(ccc2N1)-c1cccnc1

InChI Key: InChIKey=MPGBYGNPFRLHAO-UHFFFAOYSA-N

Data: 12 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 12 hits for monomerid = 50000306   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Thromboxane-A synthase (Human)	BDBM50000306 (6-Pyridin-3-yl-3,4-dihydro-1H-quinolin-2-one | CHE...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	540	n/a	n/a	n/a	n/a	n/a	n/a
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cGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B (Human)	BDBM50000306 (6-Pyridin-3-yl-3,4-dihydro-1H-quinolin-2-one | CHE...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 11B2, mitochondrial (Human)	BDBM50000306 (6-Pyridin-3-yl-3,4-dihydro-1H-quinolin-2-one | CHE...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	28	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 1A2 (Human)	BDBM50000306 (6-Pyridin-3-yl-3,4-dihydro-1H-quinolin-2-one | CHE...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.95E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 2C9 (Human)	BDBM50000306 (6-Pyridin-3-yl-3,4-dihydro-1H-quinolin-2-one | CHE...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5.89E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 2D6 (Human)	BDBM50000306 (6-Pyridin-3-yl-3,4-dihydro-1H-quinolin-2-one | CHE...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.71E+5	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 3A4 (Human)	BDBM50000306 (6-Pyridin-3-yl-3,4-dihydro-1H-quinolin-2-one | CHE...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.27E+5	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 11B1, mitochondrial (Human)	BDBM50000306 (6-Pyridin-3-yl-3,4-dihydro-1H-quinolin-2-one | CHE...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	6.75E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 11B2, mitochondrial (Human)	BDBM50000306 (6-Pyridin-3-yl-3,4-dihydro-1H-quinolin-2-one | CHE...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	28	n/a	n/a	n/a	n/a	n/a	n/a
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Aromatase (Human)	BDBM50000306 (6-Pyridin-3-yl-3,4-dihydro-1H-quinolin-2-one | CHE...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 11B2, mitochondrial (Human)	BDBM50000306 (6-Pyridin-3-yl-3,4-dihydro-1H-quinolin-2-one | CHE...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	28	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 11B1, mitochondrial (Human)	BDBM50000306 (6-Pyridin-3-yl-3,4-dihydro-1H-quinolin-2-one | CHE...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	6.75E+3	n/a	n/a	n/a	n/a	n/a	n/a
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