BDBM50000308 6-(Imidazol-1-yl-phenyl-methyl)-3,4-dihydro-1H-quinolin-2-one::CHEMBL158201

SMILES O=C1CCc2cc(ccc2N1)C(c1ccccc1)n1ccnc1

InChI Key InChIKey=RVFWZZNOQSIYGX-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50000308   

TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B(Homo sapiens (Human))
Syntex Research

Curated by ChEMBL
LigandPNGBDBM50000308(6-(Imidazol-1-yl-phenyl-methyl)-3,4-dihydro-1H-qui...)
Affinity DataIC50:  4.00E+4nMAssay Description:Inhibition of human blood platelet c-AMP phosphodiesteraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThromboxane-A synthase(Homo sapiens (Human))
Syntex Research

Curated by ChEMBL
LigandPNGBDBM50000308(6-(Imidazol-1-yl-phenyl-methyl)-3,4-dihydro-1H-qui...)
Affinity DataIC50:  350nMAssay Description:Compound was evaluated for the inhibition of human blood platelet,thromboxane A2 synthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed