BDBM50000540 1-(3-Trifluoromethyl-phenyl)-4,5-dihydro-1H-pyrazol-3-ylamine::1-(3-Trifluoromethyl-phenyl)-4,5-dihydro-1H-pyrazol-3-ylamine (BW-755C)::1-(3-Trifluoromethyl-phenyl)-4,5-dihydro-1H-pyrazol-3-ylamine(BW 755 C)::1-(3-Trifluoromethyl-phenyl)-4,5-dihydro-1H-pyrazol-3-ylamine(BW 755C)::1-(3-trifluoromethylphenyl)-4,5-dihydro-1H-3-pyrazolamine::BW-755C::CHEMBL274642

SMILES: NC1=NN(CC1)c1cccc(c1)C(F)(F)F

InChI Key: InChIKey=CPXGGWXJNQSFEP-UHFFFAOYSA-N

Data: 26 IC50  2 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 28 hits for monomerid = 50000540   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Polyunsaturated fatty acid 5-lipoxygenase (Rat)	BDBM50000540 (1-(3-Trifluoromethyl-phenyl)-4,5-dihydro-1H-pyrazo...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Rat)	BDBM50000540 (1-(3-Trifluoromethyl-phenyl)-4,5-dihydro-1H-pyrazo...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Human)	BDBM50000540 (1-(3-Trifluoromethyl-phenyl)-4,5-dihydro-1H-pyrazo...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	1.30E+5	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1/2 (Rat)	BDBM50000540 (1-(3-Trifluoromethyl-phenyl)-4,5-dihydro-1H-pyrazo...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Human)	BDBM50000540 (1-(3-Trifluoromethyl-phenyl)-4,5-dihydro-1H-pyrazo...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	6.80E+3	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Human)	BDBM50000540 (1-(3-Trifluoromethyl-phenyl)-4,5-dihydro-1H-pyrazo...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1/2 (Human)	BDBM50000540 (1-(3-Trifluoromethyl-phenyl)-4,5-dihydro-1H-pyrazo...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Rat)	BDBM50000540 (1-(3-Trifluoromethyl-phenyl)-4,5-dihydro-1H-pyrazo...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Rat)	BDBM50000540 (1-(3-Trifluoromethyl-phenyl)-4,5-dihydro-1H-pyrazo...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Rat)	BDBM50000540 (1-(3-Trifluoromethyl-phenyl)-4,5-dihydro-1H-pyrazo...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	890	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Phospholipase A2 (Rat)	BDBM50000540 (1-(3-Trifluoromethyl-phenyl)-4,5-dihydro-1H-pyrazo...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>2.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Rat)	BDBM50000540 (1-(3-Trifluoromethyl-phenyl)-4,5-dihydro-1H-pyrazo...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1/2 (Sheep)	BDBM50000540 (1-(3-Trifluoromethyl-phenyl)-4,5-dihydro-1H-pyrazo...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1/2 (Rat)	BDBM50000540 (1-(3-Trifluoromethyl-phenyl)-4,5-dihydro-1H-pyrazo...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	800	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Rat)	BDBM50000540 (1-(3-Trifluoromethyl-phenyl)-4,5-dihydro-1H-pyrazo...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid lipoxygenase ALOX15 (Human)	BDBM50000540 (1-(3-Trifluoromethyl-phenyl)-4,5-dihydro-1H-pyrazo...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.13E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Rat)	BDBM50000540 (1-(3-Trifluoromethyl-phenyl)-4,5-dihydro-1H-pyrazo...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Human)	BDBM50000540 (1-(3-Trifluoromethyl-phenyl)-4,5-dihydro-1H-pyrazo...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1/2 (Human)	BDBM50000540 (1-(3-Trifluoromethyl-phenyl)-4,5-dihydro-1H-pyrazo...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	9.70E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1/2 (Human)	BDBM50000540 (1-(3-Trifluoromethyl-phenyl)-4,5-dihydro-1H-pyrazo...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Human)	BDBM50000540 (1-(3-Trifluoromethyl-phenyl)-4,5-dihydro-1H-pyrazo...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	7.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Rat)	BDBM50000540 (1-(3-Trifluoromethyl-phenyl)-4,5-dihydro-1H-pyrazo...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Human)	BDBM50000540 (1-(3-Trifluoromethyl-phenyl)-4,5-dihydro-1H-pyrazo...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	750	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Rat)	BDBM50000540 (1-(3-Trifluoromethyl-phenyl)-4,5-dihydro-1H-pyrazo...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Rat)	BDBM50000540 (1-(3-Trifluoromethyl-phenyl)-4,5-dihydro-1H-pyrazo...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1/2 (Rat)	BDBM50000540 (1-(3-Trifluoromethyl-phenyl)-4,5-dihydro-1H-pyrazo...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	6.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Rat)	BDBM50000540 (1-(3-Trifluoromethyl-phenyl)-4,5-dihydro-1H-pyrazo...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.30E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Rat)	BDBM50000540 (1-(3-Trifluoromethyl-phenyl)-4,5-dihydro-1H-pyrazo...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair