BDBM50000597 1-[6-(4-Oxo-2-phenyl-4H-chromen-6-yloxy)-hexyl]-piperidine-4-carboxylic acid ethyl ester::CHEMBL38708

SMILES CCOC(=O)C1CCN(CCCCCCOc2ccc3oc(cc(=O)c3c2)-c2ccccc2)CC1

InChI Key InChIKey=ZXEKOBFUIBKWPJ-UHFFFAOYSA-N

Data  1 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50000597   

TargetSigma non-opioid intracellular receptor 1(Human)
Nova Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50000597(CHEMBL38708 | 1-[6-(4-Oxo-2-phenyl-4H-chromen-6-yl...)
Affinity DataIC50: 102nMAssay Description:Potency at the sigma binding site was determined in radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Human)
Nova Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50000597(CHEMBL38708 | 1-[6-(4-Oxo-2-phenyl-4H-chromen-6-yl...)
Affinity DataIC50: 164nMAssay Description:Potency at the sigma binding site was determined in radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Nova Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50000597(CHEMBL38708 | 1-[6-(4-Oxo-2-phenyl-4H-chromen-6-yl...)
Affinity DataKi:  2.80E+3nMAssay Description:Affinity towards dopamine receptor D2 was determined by competition studies using [3H]sulpiride in rat striatum.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed