BDBM50000598 2-(3-Chloro-phenyl)-6-[6-(4-hydroxy-piperidin-1-yl)-hexyloxy]-chromen-4-one::CHEMBL38514

SMILES OC1CCN(CCCCCCOc2ccc3oc(cc(=O)c3c2)-c2cccc(Cl)c2)CC1

InChI Key InChIKey=SLVDSHANYGRJLH-UHFFFAOYSA-N

Data  1 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50000598   

TargetSigma non-opioid intracellular receptor 1(Human)
Nova Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50000598(CHEMBL38514 | 2-(3-Chloro-phenyl)-6-[6-(4-hydroxy-...)
Affinity DataIC50: 156nMAssay Description:Potency at the sigma binding site was determined in radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Human)
Nova Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50000598(CHEMBL38514 | 2-(3-Chloro-phenyl)-6-[6-(4-hydroxy-...)
Affinity DataIC50: 175nMAssay Description:Potency at the sigma binding site was determined in radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Nova Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50000598(CHEMBL38514 | 2-(3-Chloro-phenyl)-6-[6-(4-hydroxy-...)
Affinity DataKi:  6.40E+3nMAssay Description:Affinity towards dopamine receptor D2 was determined by competition studies using [3H]sulpiride in rat striatum.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed