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BDBM50000718 2-{7-[4-(4-Fluoro-phenyl)-1-methyl-butyl]-5-methoxy-10,10-dimethyl-1,2,4,10-tetrahydro-9-oxa-3-aza-phenanthren-3-yl}-acetamide::CHEMBL65144

SMILES: COc1cc(cc2OC(C)(C)C3=C(CN(CC(N)=O)CC3)c12)C(C)CCCc1ccc(F)cc1

InChI Key: InChIKey=WGBUMONGBSKHGZ-UHFFFAOYNA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50000718   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Platelet activating factor receptor


(Cavia porcellus)
BDBM50000718
PNG
(2-{7-[4-(4-Fluoro-phenyl)-1-methyl-butyl]-5-methox...)
Show SMILES COc1cc(cc2OC(C)(C)C3=C(CN(CC(N)=O)CC3)c12)C(C)CCCc1ccc(F)cc1
Show InChI InChI=1/C28H35FN2O3/c1-18(6-5-7-19-8-10-21(29)11-9-19)20-14-24(33-4)27-22-16-31(17-26(30)32)13-12-23(22)28(2,3)34-25(27)15-20/h8-11,14-15,18H,5-7,12-13,16-17H2,1-4H3,(H2,30,32)
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Similars

Article
PubMed
945n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
In vitro intrinsic binding affinity at platelet activating factor receptor using rabbit platelet membranes


J Med Chem 35: 2055-61 (1992)


Article DOI: 10.1021/jm00089a016
BindingDB Entry DOI: 10.7270/Q2NZ86K9
More data for this
Ligand-Target Pair