BDBM50000787 (1S,5R,13R,17S)-4-(cyclopropylmethyl)-10,17-dihydroxy-12-oxa-4-azapentacyclo[9.6.1.0^{1,13}.0^{5,17}.0^{7,18}]octadeca-7(18),8,10-trien-14-one::NALTREXONE

SMILES: Oc1ccc2C[C@H]3N(CC4CC4)CC[C@@]45[C@@H](Oc1c24)C(=O)CC[C@@]35O

InChI Key: InChIKey=DQCKKXVULJGBQN-UHFFFAOYSA-N

Data: 20 KI  5 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 25 hits for monomerid = 50000787   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Neuronal acetylcholine receptor subunit alpha-4 (Rat)	BDBM50000787 ((1S,5R,13R,17S)-4-(cyclopropylmethyl)-10,17-dihydr...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.41E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Neuronal acetylcholine receptor subunit alpha-7 (Human)	BDBM50000787 ((1S,5R,13R,17S)-4-(cyclopropylmethyl)-10,17-dihydr...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-4 (Rat)	BDBM50000787 ((1S,5R,13R,17S)-4-(cyclopropylmethyl)-10,17-dihydr...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.39E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-7 (Human)	BDBM50000787 ((1S,5R,13R,17S)-4-(cyclopropylmethyl)-10,17-dihydr...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-4 (Rat)	BDBM50000787 ((1S,5R,13R,17S)-4-(cyclopropylmethyl)-10,17-dihydr...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.10E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Human)	BDBM50000787 ((1S,5R,13R,17S)-4-(cyclopropylmethyl)-10,17-dihydr...) Show SMILES Show InChI	GoogleScholar	UniChem		0.0420	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Rat)	BDBM50000787 ((1S,5R,13R,17S)-4-(cyclopropylmethyl)-10,17-dihydr...) Show SMILES Show InChI	GoogleScholar	UniChem		0.0825	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Human)	BDBM50000787 ((1S,5R,13R,17S)-4-(cyclopropylmethyl)-10,17-dihydr...) Show SMILES Show InChI	GoogleScholar	UniChem		0.300	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Rat)	BDBM50000787 ((1S,5R,13R,17S)-4-(cyclopropylmethyl)-10,17-dihydr...) Show SMILES Show InChI	GoogleScholar	UniChem		0.460	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Rat)	BDBM50000787 ((1S,5R,13R,17S)-4-(cyclopropylmethyl)-10,17-dihydr...) Show SMILES Show InChI	GoogleScholar	UniChem		0.509	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Mouse)	BDBM50000787 ((1S,5R,13R,17S)-4-(cyclopropylmethyl)-10,17-dihydr...) Show SMILES Show InChI	GoogleScholar	UniChem		0.646	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Human)	BDBM50000787 ((1S,5R,13R,17S)-4-(cyclopropylmethyl)-10,17-dihydr...) Show SMILES Show InChI	GoogleScholar	UniChem		0.740	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Human)	BDBM50000787 ((1S,5R,13R,17S)-4-(cyclopropylmethyl)-10,17-dihydr...) Show SMILES Show InChI	GoogleScholar	UniChem		0.810	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Rat)	BDBM50000787 ((1S,5R,13R,17S)-4-(cyclopropylmethyl)-10,17-dihydr...) Show SMILES Show InChI	GoogleScholar	UniChem		1.07	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Human)	BDBM50000787 ((1S,5R,13R,17S)-4-(cyclopropylmethyl)-10,17-dihydr...) Show SMILES Show InChI	GoogleScholar	UniChem		2	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Human)	BDBM50000787 ((1S,5R,13R,17S)-4-(cyclopropylmethyl)-10,17-dihydr...) Show SMILES Show InChI	GoogleScholar	UniChem		3.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Delta-type opioid receptor (Rat)	BDBM50000787 ((1S,5R,13R,17S)-4-(cyclopropylmethyl)-10,17-dihydr...) Show SMILES Show InChI	GoogleScholar	UniChem		8.02	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Human)	BDBM50000787 ((1S,5R,13R,17S)-4-(cyclopropylmethyl)-10,17-dihydr...) Show SMILES Show InChI	GoogleScholar	UniChem		10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Delta-type opioid receptor (Rat)	BDBM50000787 ((1S,5R,13R,17S)-4-(cyclopropylmethyl)-10,17-dihydr...) Show SMILES Show InChI	GoogleScholar	UniChem		11	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Delta-type opioid receptor (Human)	BDBM50000787 ((1S,5R,13R,17S)-4-(cyclopropylmethyl)-10,17-dihydr...) Show SMILES Show InChI	GoogleScholar	UniChem		16	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Delta-type opioid receptor (Human)	BDBM50000787 ((1S,5R,13R,17S)-4-(cyclopropylmethyl)-10,17-dihydr...) Show SMILES Show InChI	GoogleScholar	UniChem		25	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Delta-type opioid receptor (Human)	BDBM50000787 ((1S,5R,13R,17S)-4-(cyclopropylmethyl)-10,17-dihydr...) Show SMILES Show InChI	GoogleScholar	UniChem		67	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Nociceptin receptor (Human)	BDBM50000787 ((1S,5R,13R,17S)-4-(cyclopropylmethyl)-10,17-dihydr...) Show SMILES Show InChI	GoogleScholar	UniChem		>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Norepinephrine transporter (Rat)	BDBM50000787 ((1S,5R,13R,17S)-4-(cyclopropylmethyl)-10,17-dihydr...) Show SMILES Show InChI	GoogleScholar	UniChem		>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Sodium-dependent serotonin transporter (Rat)	BDBM50000787 ((1S,5R,13R,17S)-4-(cyclopropylmethyl)-10,17-dihydr...) Show SMILES Show InChI	GoogleScholar	UniChem		>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair