BDBM50000788 (morphine)4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol::(naloxone) 4-allyl-10,17-dihydroxy-(1S,5R,13R,17S)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10-trien-14-one::(naloxone)4-allyl-10,17-dihydroxy-(1S,5R,13R,17S)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10-trien-14-one::(naloxone)4-allyl-10,17-dihydroxy-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10-trien-14-one::4-allyl-10,17-dihydroxy-(1S,5R,13R,17S)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10-trien-14-one::4-allyl-10,17-dihydroxy-(1S,5R,13R,17S)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10-trien-14-one (naloxone)::4-allyl-10,17-dihydroxy-(1S,5R,13R,17S)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10-trien-14-one( Naloxone)::4-allyl-10,17-dihydroxy-(1S,5R,13R,17S)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10-trien-14-one(Naxolone)::4-allyl-10,17-dihydroxy-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10-trien-14-one::4-allyl-10,17-dihydroxy-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10-trien-14-one(naloxone)C2H2O4::Analog of 14-(Arylhydroxyamino)codeinone::NALOXONE::NARCAN::SUBOXONE::[17-(2,3-3H-2-propenyl)]-4, 5a -epoxy-3,14-dihydroxymorphinan-6-one

SMILES: C=CCN1CC[C@]23c4c5ccc(c4O[C@H]2C(=O)CC[C@]3([C@H]1C5)O)O

InChI Key: InChIKey=UZHSEJADLWPNLE-UHFFFAOYSA-N

Data: 147 KI  52 IC50  10 Kd  3 EC50

PDB links: 1 PDB ID matches this monomer.

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 213 hits for monomerid = 50000788   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Kappa-type opioid receptor (Human)	BDBM50000788 ([17-(2,3-3H-2-propenyl)]-4, 5a -epoxy-3,14-dihydro...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	704	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Bile salt export pump (Human)	BDBM50000788 ([17-(2,3-3H-2-propenyl)]-4, 5a -epoxy-3,14-dihydro...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5.49E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Bile salt export pump (Human)	BDBM50000788 ([17-(2,3-3H-2-propenyl)]-4, 5a -epoxy-3,14-dihydro...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.33E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
ATP-binding cassette sub-family C member 3 (Human)	BDBM50000788 ([17-(2,3-3H-2-propenyl)]-4, 5a -epoxy-3,14-dihydro...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.33E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
ATP-binding cassette sub-family C member 2 (Human)	BDBM50000788 ([17-(2,3-3H-2-propenyl)]-4, 5a -epoxy-3,14-dihydro...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.33E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
ATP-binding cassette sub-family C member 4 (Human)	BDBM50000788 ([17-(2,3-3H-2-propenyl)]-4, 5a -epoxy-3,14-dihydro...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.33E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Human)	BDBM50000788 ([17-(2,3-3H-2-propenyl)]-4, 5a -epoxy-3,14-dihydro...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	45	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Human)	BDBM50000788 ([17-(2,3-3H-2-propenyl)]-4, 5a -epoxy-3,14-dihydro...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	45	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Delta-type/Kappa-type/Mu-type opioid receptor (Rat)	BDBM50000788 ([17-(2,3-3H-2-propenyl)]-4, 5a -epoxy-3,14-dihydro...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	1.5	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Delta-type/Kappa-type/Mu-type opioid receptor (Rat)	BDBM50000788 ([17-(2,3-3H-2-propenyl)]-4, 5a -epoxy-3,14-dihydro...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Delta-type/Kappa-type/Mu-type opioid receptor (Human)	BDBM50000788 ([17-(2,3-3H-2-propenyl)]-4, 5a -epoxy-3,14-dihydro...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5.5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Mouse)	BDBM50000788 ([17-(2,3-3H-2-propenyl)]-4, 5a -epoxy-3,14-dihydro...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	15	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Delta-type opioid receptor (Human)	BDBM50000788 ([17-(2,3-3H-2-propenyl)]-4, 5a -epoxy-3,14-dihydro...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	78	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Delta-type opioid receptor (Human)	BDBM50000788 ([17-(2,3-3H-2-propenyl)]-4, 5a -epoxy-3,14-dihydro...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	146	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Delta-type opioid receptor (Human)	BDBM50000788 ([17-(2,3-3H-2-propenyl)]-4, 5a -epoxy-3,14-dihydro...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	153	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Human)	BDBM50000788 ([17-(2,3-3H-2-propenyl)]-4, 5a -epoxy-3,14-dihydro...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	140	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Human)	BDBM50000788 ([17-(2,3-3H-2-propenyl)]-4, 5a -epoxy-3,14-dihydro...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	302	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Human)	BDBM50000788 ([17-(2,3-3H-2-propenyl)]-4, 5a -epoxy-3,14-dihydro...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	27	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Human)	BDBM50000788 ([17-(2,3-3H-2-propenyl)]-4, 5a -epoxy-3,14-dihydro...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	722	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cytochrome b-245 heavy chain (Human)	BDBM50000788 ([17-(2,3-3H-2-propenyl)]-4, 5a -epoxy-3,14-dihydro...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.96E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Human)	BDBM50000788 ([17-(2,3-3H-2-propenyl)]-4, 5a -epoxy-3,14-dihydro...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	8.60	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
C-C chemokine receptor type 5 (Mouse)	BDBM50000788 ([17-(2,3-3H-2-propenyl)]-4, 5a -epoxy-3,14-dihydro...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	21	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
C-C chemokine receptor type 5 (Mouse)	BDBM50000788 ([17-(2,3-3H-2-propenyl)]-4, 5a -epoxy-3,14-dihydro...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Rat)	BDBM50000788 ([17-(2,3-3H-2-propenyl)]-4, 5a -epoxy-3,14-dihydro...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Rat)	BDBM50000788 ([17-(2,3-3H-2-propenyl)]-4, 5a -epoxy-3,14-dihydro...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	4.5	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Human)	BDBM50000788 ([17-(2,3-3H-2-propenyl)]-4, 5a -epoxy-3,14-dihydro...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	7.30	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Delta-type opioid receptor/Kappa-type opioid receptor/Mu-type opioid receptor/Sigma non-opioid intracellular receptor 1 (Rat)	BDBM50000788 ([17-(2,3-3H-2-propenyl)]-4, 5a -epoxy-3,14-dihydro...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	154	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Rat)	BDBM50000788 ([17-(2,3-3H-2-propenyl)]-4, 5a -epoxy-3,14-dihydro...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	0.400	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Rat)	BDBM50000788 ([17-(2,3-3H-2-propenyl)]-4, 5a -epoxy-3,14-dihydro...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	0.400	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Rat)	BDBM50000788 ([17-(2,3-3H-2-propenyl)]-4, 5a -epoxy-3,14-dihydro...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Delta-type opioid receptor (Rat)	BDBM50000788 ([17-(2,3-3H-2-propenyl)]-4, 5a -epoxy-3,14-dihydro...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	18	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Bovine)	BDBM50000788 ([17-(2,3-3H-2-propenyl)]-4, 5a -epoxy-3,14-dihydro...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Guinea pig)	BDBM50000788 ([17-(2,3-3H-2-propenyl)]-4, 5a -epoxy-3,14-dihydro...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	8.90	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Delta-type opioid receptor (Human)	BDBM50000788 ([17-(2,3-3H-2-propenyl)]-4, 5a -epoxy-3,14-dihydro...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	62	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Guinea pig)	BDBM50000788 ([17-(2,3-3H-2-propenyl)]-4, 5a -epoxy-3,14-dihydro...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Delta-type/Kappa-type/Mu-type opioid receptor (Human)	BDBM50000788 ([17-(2,3-3H-2-propenyl)]-4, 5a -epoxy-3,14-dihydro...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	43	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Delta-type opioid receptor (Human)	BDBM50000788 ([17-(2,3-3H-2-propenyl)]-4, 5a -epoxy-3,14-dihydro...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	62	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Guinea pig)	BDBM50000788 ([17-(2,3-3H-2-propenyl)]-4, 5a -epoxy-3,14-dihydro...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	8.90	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Guinea pig)	BDBM50000788 ([17-(2,3-3H-2-propenyl)]-4, 5a -epoxy-3,14-dihydro...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Delta-type/Kappa-type/Mu-type opioid receptor (Human)	BDBM50000788 ([17-(2,3-3H-2-propenyl)]-4, 5a -epoxy-3,14-dihydro...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	43	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Human)	BDBM50000788 ([17-(2,3-3H-2-propenyl)]-4, 5a -epoxy-3,14-dihydro...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Human)	BDBM50000788 ([17-(2,3-3H-2-propenyl)]-4, 5a -epoxy-3,14-dihydro...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Delta-type opioid receptor (Human)	BDBM50000788 ([17-(2,3-3H-2-propenyl)]-4, 5a -epoxy-3,14-dihydro...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	151	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Human)	BDBM50000788 ([17-(2,3-3H-2-propenyl)]-4, 5a -epoxy-3,14-dihydro...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Human)	BDBM50000788 ([17-(2,3-3H-2-propenyl)]-4, 5a -epoxy-3,14-dihydro...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Human)	BDBM50000788 ([17-(2,3-3H-2-propenyl)]-4, 5a -epoxy-3,14-dihydro...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Human)	BDBM50000788 ([17-(2,3-3H-2-propenyl)]-4, 5a -epoxy-3,14-dihydro...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	6.60	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Rat)	BDBM50000788 ([17-(2,3-3H-2-propenyl)]-4, 5a -epoxy-3,14-dihydro...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.60	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Human)	BDBM50000788 ([17-(2,3-3H-2-propenyl)]-4, 5a -epoxy-3,14-dihydro...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	7.30	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Human)	BDBM50000788 ([17-(2,3-3H-2-propenyl)]-4, 5a -epoxy-3,14-dihydro...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	7.30	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair