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BDBM50000821 2-[3-(1-Methoxy-cyclohexyl)-phenoxymethyl]-naphthalene::CHEMBL87670

SMILES: COC1(CCCCC1)c1cccc(OCc2ccc3ccccc3c2)c1

InChI Key: InChIKey=UVUNOGVKWSTXDF-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50000821   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Arachidonate 5-lipoxygenase


(Homo sapiens (Human))
BDBM50000821
PNG
(2-[3-(1-Methoxy-cyclohexyl)-phenoxymethyl]-naphtha...)
Show SMILES COC1(CCCCC1)c1cccc(OCc2ccc3ccccc3c2)c1
Show InChI InChI=1S/C24H26O2/c1-25-24(14-5-2-6-15-24)22-10-7-11-23(17-22)26-18-19-12-13-20-8-3-4-9-21(20)16-19/h3-4,7-13,16-17H,2,5-6,14-15,18H2,1H3
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Similars

Article
PubMed
n/an/a 2.60E+3n/an/an/an/an/an/a



ICI Pharmaceuticals Group

Curated by ChEMBL


Assay Description
In vitro inhibition of leukotriene B4 synthesis in human whole blood by inhibiting 5-lipoxygenase


J Med Chem 35: 2600-9 (1992)


Article DOI: 10.1021/jm00092a010
BindingDB Entry DOI: 10.7270/Q2Q240VJ
More data for this
Ligand-Target Pair