BDBM50001183 3-[5-(4-Chloro-phenyl)-1-(4-methoxy-phenyl)-1H-pyrazol-3-yl]-N-hydroxy-N-methyl-propionamide::CHEMBL316040::Tepoxalin

SMILES: COc1ccc(cc1)-n1nc(CCC(=O)N(C)O)cc1-c1ccc(Cl)cc1

InChI Key: InChIKey=XYKWNRUXCOIMFZ-UHFFFAOYSA-N

Data: 8 IC50  1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50001183   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Prostaglandin G/H synthase 1 (Sheep)	BDBM50001183 (3-[5-(4-Chloro-phenyl)-1-(4-methoxy-phenyl)-1H-pyr...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Rat)	BDBM50001183 (3-[5-(4-Chloro-phenyl)-1-(4-methoxy-phenyl)-1H-pyr...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1/2 (Rat)	BDBM50001183 (3-[5-(4-Chloro-phenyl)-1-(4-methoxy-phenyl)-1H-pyr...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Rat)	BDBM50001183 (3-[5-(4-Chloro-phenyl)-1-(4-methoxy-phenyl)-1H-pyr...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1/2 (Rat)	BDBM50001183 (3-[5-(4-Chloro-phenyl)-1-(4-methoxy-phenyl)-1H-pyr...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.85E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1 (Sheep)	BDBM50001183 (3-[5-(4-Chloro-phenyl)-1-(4-methoxy-phenyl)-1H-pyr...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.85E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Human)	BDBM50001183 (3-[5-(4-Chloro-phenyl)-1-(4-methoxy-phenyl)-1H-pyr...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.85E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Rat)	BDBM50001183 (3-[5-(4-Chloro-phenyl)-1-(4-methoxy-phenyl)-1H-pyr...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	150	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Human)	BDBM50001183 (3-[5-(4-Chloro-phenyl)-1-(4-methoxy-phenyl)-1H-pyr...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	70	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair