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BDBM50001187 3-(5-Chloro-benzothiazol-2-ylsulfanyl)-N-hydroxy-N-methyl-propionamide::CHEMBL110928

SMILES: CN(O)C(=O)CCSc1nc2cc(Cl)ccc2s1

InChI Key: InChIKey=VHIXZILPCANJJA-UHFFFAOYSA-N

Data: 1 EC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50001187   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Arachidonate 5-lipoxygenase


(Homo sapiens (Human))
BDBM50001187
PNG
(3-(5-Chloro-benzothiazol-2-ylsulfanyl)-N-hydroxy-N...)
Show SMILES CN(O)C(=O)CCSc1nc2cc(Cl)ccc2s1
Show InChI InChI=1S/C11H11ClN2O2S2/c1-14(16)10(15)4-5-17-11-13-8-6-7(12)2-3-9(8)18-11/h2-3,6,16H,4-5H2,1H3
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MMDB

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Similars

Article
PubMed
n/an/an/an/a 20n/an/an/an/a



R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
In vitro inhibition of ionophore stimulated LTB4 release from human peripheral blood leukocytes.


J Med Chem 35: 3180-3 (1992)


Article DOI: 10.1021/jm00095a012
BindingDB Entry DOI: 10.7270/Q2542P68
More data for this
Ligand-Target Pair