BDBM50001254 1-(8-Methoxy-4-o-tolylamino-quinolin-3-yl)-butan-1-one::CHEMBL327717::SK&F-96067::SK-96067

SMILES CCCC(=O)c1cnc2c(OC)cccc2c1Nc1ccccc1C

InChI Key InChIKey=MAVJDLHBPIXVJL-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50001254   

TargetPotassium-transporting ATPase alpha chain 1/subunit beta(Sus scrofa (Pig))
Smithkline Beecham Pharmaceuticals R&D

Curated by ChEMBL
LigandPNGBDBM50001254(1-(8-Methoxy-4-o-tolylamino-quinolin-3-yl)-butan-1...)
Affinity DataIC50:  1.70E+3nMpH: 7.0Assay Description:Inhibition of K+ -stimulated gastric ATPase activity was measured using lyophilized gastric vesicles at pH 7More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium-transporting ATPase alpha chain 1/subunit beta(Homo sapiens (Human))
Korea Research Institute Of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50001254(1-(8-Methoxy-4-o-tolylamino-quinolin-3-yl)-butan-1...)
Affinity DataIC50:  1.80E+4nMAssay Description:Compound was tested in vitro for H+/K+ ATPase activity in rabbit stomach preparationsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium-transporting ATPase alpha chain 1/subunit beta(Sus scrofa (Pig))
Smithkline Beecham Pharmaceuticals R&D

Curated by ChEMBL
LigandPNGBDBM50001254(1-(8-Methoxy-4-o-tolylamino-quinolin-3-yl)-butan-1...)
Affinity DataIC50:  1.05E+3nMAssay Description:Concentration required to inhibit the activity of K+ stimulated gastric ATPaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed