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BDBM50001338 1'-methylsulfonylspiro[1H-indene-1,4'-(hexahydropyridine)]::CHEMBL126773

SMILES: CS(=O)(=O)N1CCC2(CC1)C=Cc1ccccc21

InChI Key: InChIKey=SJFJQACKCDPJDX-UHFFFAOYSA-N

Data: 3 IC50

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   Substructure
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50001338   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Oxytocin receptor


(RAT)
BDBM50001338
PNG
(1'-methylsulfonylspiro[1H-indene-1,4'-(hexahydropy...)
Show SMILES CS(=O)(=O)N1CCC2(CC1)C=Cc1ccccc21
Show InChI InChI=1S/C14H17NO2S/c1-18(16,17)15-10-8-14(9-11-15)7-6-12-4-2-3-5-13(12)14/h2-7H,8-11H2,1H3
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a>1.00E+5n/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Half-maximal inhibition of binding of [3H]-Oxytocin to OT receptor in rat uterine tissue


J Med Chem 35: 3919-27 (1992)


Article DOI: 10.1021/jm00099a020
BindingDB Entry DOI: 10.7270/Q2N015G7
More data for this
Ligand-Target Pair
Vasopressin receptor


(RAT-Rattus norvegicus (Rat))
BDBM50001338
PNG
(1'-methylsulfonylspiro[1H-indene-1,4'-(hexahydropy...)
Show SMILES CS(=O)(=O)N1CCC2(CC1)C=Cc1ccccc21
Show InChI InChI=1S/C14H17NO2S/c1-18(16,17)15-10-8-14(9-11-15)7-6-12-4-2-3-5-13(12)14/h2-7H,8-11H2,1H3
UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a>1.00E+5n/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Half-maximal inhibition of binding of [3H]- vasopressin to the vasopressin receptor 2 in rat kidney


J Med Chem 35: 3919-27 (1992)


Article DOI: 10.1021/jm00099a020
BindingDB Entry DOI: 10.7270/Q2N015G7
More data for this
Ligand-Target Pair
Vasopressin receptor


(RAT-Rattus norvegicus (Rat))
BDBM50001338
PNG
(1'-methylsulfonylspiro[1H-indene-1,4'-(hexahydropy...)
Show SMILES CS(=O)(=O)N1CCC2(CC1)C=Cc1ccccc21
Show InChI InChI=1S/C14H17NO2S/c1-18(16,17)15-10-8-14(9-11-15)7-6-12-4-2-3-5-13(12)14/h2-7H,8-11H2,1H3
UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a>1.00E+5n/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Half-maximal inhibition of binding of [3H]vasopressin to vasopressin receptor 1 in rat liver


J Med Chem 35: 3919-27 (1992)


Article DOI: 10.1021/jm00099a020
BindingDB Entry DOI: 10.7270/Q2N015G7
More data for this
Ligand-Target Pair