BDBM50001494 1-Butyl-3-methyl-3,7-dihydro-purine-2,6-dione::CHEMBL130503

SMILES CCCCn1c(=O)n(C)c2nc[nH]c2c1=O

InChI Key InChIKey=GDRIWEXJHHARCU-UHFFFAOYSA-N

Data  2 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50001494   

TargetAdenosine receptor A1(Guinea pig)
Hokuriku University

Curated by ChEMBL
LigandPNGBDBM50001494(CHEMBL130503 | 1-Butyl-3-methyl-3,7-dihydro-purine...)
Affinity DataKi:  4.30E+3nMAssay Description:Affinity against adenosine A1 receptor in the brain membranes by the displacement of [3H]CPX.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
Hokuriku University

Curated by ChEMBL
LigandPNGBDBM50001494(CHEMBL130503 | 1-Butyl-3-methyl-3,7-dihydro-purine...)
Affinity DataEC50:  7.60E+3nMAssay Description:Relaxant activity on the spontaneous tone of isolated guinea pig tracheal ring chains.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Human)
Hokuriku University

Curated by ChEMBL
LigandPNGBDBM50001494(CHEMBL130503 | 1-Butyl-3-methyl-3,7-dihydro-purine...)
Affinity DataKi:  1.91E+4nMAssay Description:Inhibition of c-AMP phosphodiesterase activity in guinea pig tracheal muscleMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed