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BDBM50001621 6-(7-Chloro-4-phenyl-quinolin-2-yloxy)-2,2-dimethyl-hexanoic acid::CHEMBL335142

SMILES: CC(C)(CCCCOc1cc(-c2ccccc2)c2ccc(Cl)cc2n1)C(O)=O

InChI Key: InChIKey=DBLOTMYQCUTYMX-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50001621   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
LTB4R


(HUMAN)
BDBM50001621
PNG
(6-(7-Chloro-4-phenyl-quinolin-2-yloxy)-2,2-dimethy...)
Show SMILES CC(C)(CCCCOc1cc(-c2ccccc2)c2ccc(Cl)cc2n1)C(O)=O
Show InChI InChI=1S/C23H24ClNO3/c1-23(2,22(26)27)12-6-7-13-28-21-15-19(16-8-4-3-5-9-16)18-11-10-17(24)14-20(18)25-21/h3-5,8-11,14-15H,6-7,12-13H2,1-2H3,(H,26,27)
UniProtKB/SwissProt

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PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 2.00E+3n/an/an/an/an/an/a



Centre de Recherche de Vitry-Alfortville

Curated by ChEMBL


Assay Description
Inhibition of [3H]-LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes


J Med Chem 35: 4306-14 (1992)


Article DOI: 10.1021/jm00101a007
BindingDB Entry DOI: 10.7270/Q2VH5MS6
More data for this
Ligand-Target Pair