BDBM50001655 6-(4-Benzo[1,3]dioxol-5-yl-6-phenyl-pyridin-2-yloxy)-2,2-dimethyl-hexanoic acid::CHEMBL137330

SMILES CC(C)(CCCCOc1cc(cc(n1)-c1ccccc1)-c1ccc2OCOc2c1)C(O)=O

InChI Key InChIKey=BHZGPWWJYFBUPW-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50001655   

TargetLeukotriene B4 receptor 1(Human)
Centre De Recherche De Vitry-Alfortville

Curated by ChEMBL
LigandPNGBDBM50001655(CHEMBL137330 | 6-(4-Benzo[1,3]dioxol-5-yl-6-phenyl...)
Affinity DataIC50: 7nMAssay Description:Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetLeukotriene B4 receptor 1(Human)
Centre De Recherche De Vitry-Alfortville

Curated by ChEMBL
LigandPNGBDBM50001655(CHEMBL137330 | 6-(4-Benzo[1,3]dioxol-5-yl-6-phenyl...)
Affinity DataIC50: 20nMAssay Description:Inhibition of [3H]-LTB4 binding to Leukotriene B4 receptor in the human polymorphonuclear leukocytes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetLeukotriene B4 receptor 1(Human)
Centre De Recherche De Vitry-Alfortville

Curated by ChEMBL
LigandPNGBDBM50001655(CHEMBL137330 | 6-(4-Benzo[1,3]dioxol-5-yl-6-phenyl...)
Affinity DataIC50: 120nMAssay Description:Inhibition of LTB4-induced elastase release in human polymorphonuclear leukocytesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed