BDBM50001705 CHEMBL343167::methyl 2-[4-cyclopropylmethyl-17-hydroxy-14-oxo-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7,9,11(18)-trien-10-yloxymethyl]acrylate

SMILES COC(=O)C(=C)COc1ccc2C[C@H]3N(CC4CC4)CC[C@@]45[C@@H](Oc1c24)C(=O)CC[C@@]35O

InChI Key InChIKey=CLLKOUBFCBEXLC-CKZJNZIISA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50001705   

TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
University Of Washington

Curated by ChEMBL
LigandPNGBDBM50001705(CHEMBL343167 | methyl 2-[4-cyclopropylmethyl-17-hy...)
Affinity DataIC50:  19nMAssay Description:Inhibition of opioid receptor kappa by displacing 0.5 nM [3H]bremazocine in guinea pig brain membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type/Kappa-type/Mu-type opioid receptor(Homo sapiens (Human))
University Of Washington

Curated by ChEMBL
LigandPNGBDBM50001705(CHEMBL343167 | methyl 2-[4-cyclopropylmethyl-17-hy...)
Affinity DataIC50:  10nMAssay Description:Inhibition of total opioid receptor by displacing 0.5 nM [3H]bremazocine in guinea pig brain membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(GUINEA PIG)
University Of Washington

Curated by ChEMBL
LigandPNGBDBM50001705(CHEMBL343167 | methyl 2-[4-cyclopropylmethyl-17-hy...)
Affinity DataIC50:  1.5nMAssay Description:Inhibition of opioid receptor mu by displacing 1 nM [3H]DAGO in guinea pig brain membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
University Of Washington

Curated by ChEMBL
LigandPNGBDBM50001705(CHEMBL343167 | methyl 2-[4-cyclopropylmethyl-17-hy...)
Affinity DataIC50:  17nMAssay Description:Inhibition of Opioid receptor delta 1 by displacing 1 nM [3H]DPDPE in guinea pig brain membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed