BDBM50001765 8-chloro-6-(2-chlorophenyl)-1-methyl-4H-[1,2,4]triazolo[4,3-a][1,4]benzodiazepine::CHEMBL646::Halcion::TRIAZOLAM::US20240190889, Example Triazolam::US20240270744, Example Triazolam

SMILES: Cc1nnc2CN=C(c3ccccc3Cl)c3cc(Cl)ccc3-n12

InChI Key: InChIKey=JOFWLTCLBGQGBO-UHFFFAOYSA-N

Data: 23 KI  3 IC50  2 Kd

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 34 hits for monomerid = 50001765   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Gamma-aminobutyric acid receptor subunit alpha-1 (Human)	BDBM50001765 (Halcion | CHEMBL646 | 8-chloro-6-(2-chlorophenyl)-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a
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Gamma-aminobutyric acid receptor subunit alpha-5 (Human)	BDBM50001765 (Halcion | CHEMBL646 | 8-chloro-6-(2-chlorophenyl)-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a
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Cholecystokinin receptor type A (Rat)	BDBM50001765 (Halcion | CHEMBL646 | 8-chloro-6-(2-chlorophenyl)-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.90E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Gastrin/cholecystokinin type B receptor (Human)	BDBM50001765 (Halcion | CHEMBL646 | 8-chloro-6-(2-chlorophenyl)-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
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Platelet-activating factor receptor (Guinea pig)	BDBM50001765 (Halcion | CHEMBL646 | 8-chloro-6-(2-chlorophenyl)-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.11E+4	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-1 (Rat)	BDBM50001765 (Halcion | CHEMBL646 | 8-chloro-6-(2-chlorophenyl)-...) Show SMILES Show InChI	GoogleScholar	UniChem		0.310	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-1 (Rat)	BDBM50001765 (Halcion | CHEMBL646 | 8-chloro-6-(2-chlorophenyl)-...) Show SMILES Show InChI	GoogleScholar	UniChem		0.340	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-1 (Rat)	BDBM50001765 (Halcion | CHEMBL646 | 8-chloro-6-(2-chlorophenyl)-...) Show SMILES Show InChI	GoogleScholar	UniChem		0.450	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-1 (Rat)	BDBM50001765 (Halcion | CHEMBL646 | 8-chloro-6-(2-chlorophenyl)-...) Show SMILES Show InChI	GoogleScholar	UniChem		0.550	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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GABA-A receptor; alpha-2/beta-3/gamma-2 (Human)	BDBM50001765 (Halcion | CHEMBL646 | 8-chloro-6-(2-chlorophenyl)-...) Show SMILES Show InChI	GoogleScholar	UniChem		0.590	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-1 (Human)	BDBM50001765 (Halcion | CHEMBL646 | 8-chloro-6-(2-chlorophenyl)-...) Show SMILES Show InChI	GoogleScholar	UniChem		0.680	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-1/beta-3/gamma-2 (Human)	BDBM50001765 (Halcion | CHEMBL646 | 8-chloro-6-(2-chlorophenyl)-...) Show SMILES Show InChI	GoogleScholar	UniChem		0.800	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-5 (Human)	BDBM50001765 (Halcion | CHEMBL646 | 8-chloro-6-(2-chlorophenyl)-...) Show SMILES Show InChI	GoogleScholar	UniChem		1.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Gamma-aminobutyric acid receptor subunit alpha-2 (Human)	BDBM50001765 (Halcion | CHEMBL646 | 8-chloro-6-(2-chlorophenyl)-...) Show SMILES Show InChI	GoogleScholar	UniChem		1.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Gamma-aminobutyric acid receptor subunit alpha-3/beta-3/gamma-2 (Human)	BDBM50001765 (Halcion | CHEMBL646 | 8-chloro-6-(2-chlorophenyl)-...) Show SMILES Show InChI	GoogleScholar	UniChem		1.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-1/beta-2/gamma-1 (Human)	BDBM50001765 (Halcion | CHEMBL646 | 8-chloro-6-(2-chlorophenyl)-...) Show SMILES Show InChI	GoogleScholar	UniChem		1.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
GABA-A receptor; alpha-5/beta-3/gamma-2 (Human)	BDBM50001765 (Halcion | CHEMBL646 | 8-chloro-6-(2-chlorophenyl)-...) Show SMILES Show InChI	GoogleScholar	UniChem		1.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-1/beta-3/gamma-2 (Human)	BDBM50001765 (Halcion | CHEMBL646 | 8-chloro-6-(2-chlorophenyl)-...) Show SMILES Show InChI	GoogleScholar	UniChem		1.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-1/beta-3/gamma-2 (Human)	BDBM50001765 (Halcion | CHEMBL646 | 8-chloro-6-(2-chlorophenyl)-...) Show SMILES Show InChI	GoogleScholar	UniChem		1.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-1/beta-3/gamma-2 (Human)	BDBM50001765 (Halcion | CHEMBL646 | 8-chloro-6-(2-chlorophenyl)-...) Show SMILES Show InChI	GoogleScholar	UniChem		1.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-1 (Human)	BDBM50001765 (Halcion | CHEMBL646 | 8-chloro-6-(2-chlorophenyl)-...) Show SMILES Show InChI	GoogleScholar	UniChem		1.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-3 (Human)	BDBM50001765 (Halcion | CHEMBL646 | 8-chloro-6-(2-chlorophenyl)-...) Show SMILES Show InChI	GoogleScholar	UniChem		3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-1/beta-2/gamma-1 (Human)	BDBM50001765 (Halcion | CHEMBL646 | 8-chloro-6-(2-chlorophenyl)-...) Show SMILES Show InChI	GoogleScholar	UniChem		44.2	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-1/beta-2/gamma-1 (Human)	BDBM50001765 (Halcion | CHEMBL646 | 8-chloro-6-(2-chlorophenyl)-...) Show SMILES Show InChI	GoogleScholar	UniChem		44.2	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-1/beta-3/gamma-2 (Human)	BDBM50001765 (Halcion | CHEMBL646 | 8-chloro-6-(2-chlorophenyl)-...) Show SMILES Show InChI	GoogleScholar	UniChem		44.2	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-1/beta-2/gamma-1 (Human)	BDBM50001765 (Halcion | CHEMBL646 | 8-chloro-6-(2-chlorophenyl)-...) Show SMILES Show InChI	GoogleScholar	UniChem		44.2	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-2/beta-2/gamma-1 (Human)	BDBM50001765 (Halcion | CHEMBL646 | 8-chloro-6-(2-chlorophenyl)-...) Show SMILES Show InChI	GoogleScholar	UniChem		46.2	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-2/beta-2/gamma-1 (Human)	BDBM50001765 (Halcion | CHEMBL646 | 8-chloro-6-(2-chlorophenyl)-...) Show SMILES Show InChI	GoogleScholar	UniChem		46.2	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-2/beta-2/gamma-1 (Human)	BDBM50001765 (Halcion | CHEMBL646 | 8-chloro-6-(2-chlorophenyl)-...) Show SMILES Show InChI	GoogleScholar	UniChem		46.2	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-2/beta-2/gamma-1 (Human)	BDBM50001765 (Halcion | CHEMBL646 | 8-chloro-6-(2-chlorophenyl)-...) Show SMILES Show InChI	GoogleScholar	UniChem		46.2	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Platelet-activating factor receptor (Human)	BDBM50001765 (Halcion | CHEMBL646 | 8-chloro-6-(2-chlorophenyl)-...) Show SMILES Show InChI	GoogleScholar	UniChem		699	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Platelet-activating factor receptor (Human)	BDBM50001765 (Halcion | CHEMBL646 | 8-chloro-6-(2-chlorophenyl)-...) Show SMILES Show InChI	GoogleScholar	UniChem		2.49E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Gamma-aminobutyric acid receptor subunit alpha-6 (Human)	BDBM50001765 (Halcion | CHEMBL646 | 8-chloro-6-(2-chlorophenyl)-...) Show SMILES Show InChI	GoogleScholar	UniChem		>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-6/beta-3/gamma-2 (Human)	BDBM50001765 (Halcion | CHEMBL646 | 8-chloro-6-(2-chlorophenyl)-...) Show SMILES Show InChI	GoogleScholar	UniChem		>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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