BindingDB PrimarySearch

BDBM50001775 (ritanserin)6-(2-{4-[Bis-(4-fluoro-phenyl)-methylene]-piperidin-1-yl}-ethyl)-7-methyl-2,3-dihydro-1H-indolizin-5-one::(ritanserin)6-(2-{4-[Bis-(4-fluoro-phenyl)-methylene]-piperidin-1-yl}-ethyl)-7-methyl-thiazolo[3,2-a]pyrimidin-5-one::6-(2-(4-(bis(4-fluorophenyl)methylene)piperidin-1-yl)ethyl)-7-methyl-5H-thiazolo[3,2-a]pyrimidin-5-one::6-(2-{4-[Bis-(4-fluoro-phenyl)-methylene]-piperidin-1-yl}-ethyl)-7-methyl-8,8a-dihydro-thiazolo[3,2-a]pyrimidin-5-one::6-(2-{4-[Bis-(4-fluoro-phenyl)-methylene]-piperidin-1-yl}-ethyl)-7-methyl-thiazolo[3,2-a]pyrimidin-5-one::6-(2-{4-[Bis-(4-fluoro-phenyl)-methylene]-piperidin-1-yl}-ethyl)-7-methyl-thiazolo[3,2-a]pyrimidin-5-one (Ritanserin)::6-(2-{4-[Bis-(4-fluoro-phenyl)-methylene]-piperidin-1-yl}-ethyl)-7-methyl-thiazolo[3,2-a]pyrimidin-5-one(Ritanserin)::CHEMBL267777::RITANSERIN::Ritanserine::cid_5074

SMILES: [#6]-c1nc2sccn2c(=O)c1-[#6]-[#6]-[#7]-1-[#6]-[#6]\[#6](-[#6]-[#6]-1)=[#6](\c1ccc(F)cc1)-c1ccc(F)cc1

InChI Key: InChIKey=PSHRUZSIXFFMHV-UHFFFAOYSA-N

Data: 107 KI 32 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 139 hits for monomerid = 50001775
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Ubiquitin-conjugating enzyme E2 N (Human)	BDBM50001775 (cid_5074 \| Ritanserine \| 6-(2-{4-[Bis-(4-fluoro-ph...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Human)	BDBM50001775 (cid_5074 \| Ritanserine \| 6-(2-{4-[Bis-(4-fluoro-ph...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	0.0690	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2B (Human)	BDBM50001775 (cid_5074 \| Ritanserine \| 6-(2-{4-[Bis-(4-fluoro-ph...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Human)	BDBM50001775 (cid_5074 \| Ritanserine \| 6-(2-{4-[Bis-(4-fluoro-ph...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	4.5	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
Alpha-1A adrenergic receptor (Rat)	BDBM50001775 (cid_5074 \| Ritanserine \| 6-(2-{4-[Bis-(4-fluoro-ph...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	47	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
D(2) dopamine receptor (Rat)	BDBM50001775 (cid_5074 \| Ritanserine \| 6-(2-{4-[Bis-(4-fluoro-ph...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	12	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
Serotonin 2 (5-HT2) receptor (Rat)	BDBM50001775 (cid_5074 \| Ritanserine \| 6-(2-{4-[Bis-(4-fluoro-ph...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	0.400	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
Alpha-1A adrenergic receptor (Rat)	BDBM50001775 (cid_5074 \| Ritanserine \| 6-(2-{4-[Bis-(4-fluoro-ph...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	47	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
D(2) dopamine receptor (Rat)	BDBM50001775 (cid_5074 \| Ritanserine \| 6-(2-{4-[Bis-(4-fluoro-ph...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	12	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
Serotonin 2 (5-HT2) receptor (Rat)	BDBM50001775 (cid_5074 \| Ritanserine \| 6-(2-{4-[Bis-(4-fluoro-ph...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	0.400	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
D(2) dopamine receptor (Rat)	BDBM50001775 (cid_5074 \| Ritanserine \| 6-(2-{4-[Bis-(4-fluoro-ph...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	12	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
D(2) dopamine receptor (Rat)	BDBM50001775 (cid_5074 \| Ritanserine \| 6-(2-{4-[Bis-(4-fluoro-ph...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	12	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
Alpha-1A adrenergic receptor (Rat)	BDBM50001775 (cid_5074 \| Ritanserine \| 6-(2-{4-[Bis-(4-fluoro-ph...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	47	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Rat)	BDBM50001775 (cid_5074 \| Ritanserine \| 6-(2-{4-[Bis-(4-fluoro-ph...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	0.400	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
Diacylglycerol kinase alpha (Human)	BDBM50001775 (cid_5074 \| Ritanserine \| 6-(2-{4-[Bis-(4-fluoro-ph...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	1.67E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
Diacylglycerol kinase alpha (Human)	BDBM50001775 (cid_5074 \| Ritanserine \| 6-(2-{4-[Bis-(4-fluoro-ph...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	1.67E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
Diacylglycerol kinase alpha (Human)	BDBM50001775 (cid_5074 \| Ritanserine \| 6-(2-{4-[Bis-(4-fluoro-ph...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	>5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
Diacylglycerol kinase beta (Human)	BDBM50001775 (cid_5074 \| Ritanserine \| 6-(2-{4-[Bis-(4-fluoro-ph...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
Diacylglycerol kinase gamma (Human)	BDBM50001775 (cid_5074 \| Ritanserine \| 6-(2-{4-[Bis-(4-fluoro-ph...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
Diacylglycerol kinase zeta (Human)	BDBM50001775 (cid_5074 \| Ritanserine \| 6-(2-{4-[Bis-(4-fluoro-ph...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
Diacylglycerol kinase iota (Homo sapiens)	BDBM50001775 (cid_5074 \| Ritanserine \| 6-(2-{4-[Bis-(4-fluoro-ph...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
Diacylglycerol kinase alpha (Human)	BDBM50001775 (cid_5074 \| Ritanserine \| 6-(2-{4-[Bis-(4-fluoro-ph...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	1.51E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Rat)	BDBM50001775 (cid_5074 \| Ritanserine \| 6-(2-{4-[Bis-(4-fluoro-ph...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	1.70	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
Alpha-1A/Alpha-1B/Alpha-1D adrenergic receptor (Rat)	BDBM50001775 (cid_5074 \| Ritanserine \| 6-(2-{4-[Bis-(4-fluoro-ph...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	47	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
Serotonin 2 (5-HT2) receptor (Rat)	BDBM50001775 (cid_5074 \| Ritanserine \| 6-(2-{4-[Bis-(4-fluoro-ph...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	4.40	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
D(2) dopamine receptor (Rat)	BDBM50001775 (cid_5074 \| Ritanserine \| 6-(2-{4-[Bis-(4-fluoro-ph...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	12	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
D(2) dopamine receptor (Rat)	BDBM50001775 (cid_5074 \| Ritanserine \| 6-(2-{4-[Bis-(4-fluoro-ph...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	23	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
Alpha-1A/Alpha-1B/Alpha-1D adrenergic receptor (Rat)	BDBM50001775 (cid_5074 \| Ritanserine \| 6-(2-{4-[Bis-(4-fluoro-ph...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	37	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
Serotonin 2 (5-HT2) receptor (Rat)	BDBM50001775 (cid_5074 \| Ritanserine \| 6-(2-{4-[Bis-(4-fluoro-ph...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	1.70	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
Alpha-1A/Alpha-1B/Alpha-1D adrenergic receptor (Rat)	BDBM50001775 (cid_5074 \| Ritanserine \| 6-(2-{4-[Bis-(4-fluoro-ph...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	47	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
Serotonin 2 (5-HT2) receptor (Rat)	BDBM50001775 (cid_5074 \| Ritanserine \| 6-(2-{4-[Bis-(4-fluoro-ph...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	0.400	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
D(2) dopamine receptor (Rat)	BDBM50001775 (cid_5074 \| Ritanserine \| 6-(2-{4-[Bis-(4-fluoro-ph...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	12	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Human)	BDBM50001775 (cid_5074 \| Ritanserine \| 6-(2-{4-[Bis-(4-fluoro-ph...) Show SMILES Show InChI	GoogleScholar	UniChem	0.0100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Human)	BDBM50001775 (cid_5074 \| Ritanserine \| 6-(2-{4-[Bis-(4-fluoro-ph...) Show SMILES Show InChI	GoogleScholar	UniChem	0.0830	-12.8	n/a	n/a	n/a	n/a	n/a	n/a	4
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Rat)	BDBM50001775 (cid_5074 \| Ritanserine \| 6-(2-{4-[Bis-(4-fluoro-ph...) Show SMILES Show InChI	GoogleScholar	UniChem	0.200	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Human)	BDBM50001775 (cid_5074 \| Ritanserine \| 6-(2-{4-[Bis-(4-fluoro-ph...) Show SMILES Show InChI	GoogleScholar	UniChem	0.25	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Human)	BDBM50001775 (cid_5074 \| Ritanserine \| 6-(2-{4-[Bis-(4-fluoro-ph...) Show SMILES Show InChI	GoogleScholar	UniChem	0.25	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Human)	BDBM50001775 (cid_5074 \| Ritanserine \| 6-(2-{4-[Bis-(4-fluoro-ph...) Show SMILES Show InChI	GoogleScholar	UniChem	0.25	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
Serotonin 2 (5-HT2) receptor (Rat)	BDBM50001775 (cid_5074 \| Ritanserine \| 6-(2-{4-[Bis-(4-fluoro-ph...) Show SMILES Show InChI	GoogleScholar	UniChem	0.260	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Rat)	BDBM50001775 (cid_5074 \| Ritanserine \| 6-(2-{4-[Bis-(4-fluoro-ph...) Show SMILES Show InChI	GoogleScholar	UniChem	0.290	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Rat)	BDBM50001775 (cid_5074 \| Ritanserine \| 6-(2-{4-[Bis-(4-fluoro-ph...) Show SMILES Show InChI	GoogleScholar	UniChem	0.310	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2B (Human)	BDBM50001775 (cid_5074 \| Ritanserine \| 6-(2-{4-[Bis-(4-fluoro-ph...) Show SMILES Show InChI	GoogleScholar	UniChem	0.400	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Human)	BDBM50001775 (cid_5074 \| Ritanserine \| 6-(2-{4-[Bis-(4-fluoro-ph...) Show SMILES Show InChI	GoogleScholar	UniChem	0.440	-11.9	n/a	n/a	n/a	n/a	n/a	n/a	4
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Human)	BDBM50001775 (cid_5074 \| Ritanserine \| 6-(2-{4-[Bis-(4-fluoro-ph...) Show SMILES Show InChI	GoogleScholar	UniChem	0.450	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Human)	BDBM50001775 (cid_5074 \| Ritanserine \| 6-(2-{4-[Bis-(4-fluoro-ph...) Show SMILES Show InChI	GoogleScholar	UniChem	0.450	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Human)	BDBM50001775 (cid_5074 \| Ritanserine \| 6-(2-{4-[Bis-(4-fluoro-ph...) Show SMILES Show InChI	GoogleScholar	UniChem	0.450	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Rat)	BDBM50001775 (cid_5074 \| Ritanserine \| 6-(2-{4-[Bis-(4-fluoro-ph...) Show SMILES Show InChI	GoogleScholar	UniChem	0.540	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
Serotonin 2 (5-HT2) receptor (Rat)	BDBM50001775 (cid_5074 \| Ritanserine \| 6-(2-{4-[Bis-(4-fluoro-ph...) Show SMILES Show InChI	GoogleScholar	UniChem	0.610	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Rat)	BDBM50001775 (cid_5074 \| Ritanserine \| 6-(2-{4-[Bis-(4-fluoro-ph...) Show SMILES Show InChI	GoogleScholar	UniChem	0.631	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
Serotonin 2 (5-HT2) receptor (Rat)	BDBM50001775 (cid_5074 \| Ritanserine \| 6-(2-{4-[Bis-(4-fluoro-ph...) Show SMILES Show InChI	GoogleScholar	UniChem	0.690	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair

Displayed 1 to 50 (of 139 total ) | Next | Last >>