BDBM50001786 1-(2-{4-[5-chloro-1-(4-fluorophenyl)-1H-indol-3-yl]piperidin-1-yl}ethyl)imidazolidin-2-one::1-[2-[4-[5-chloro-1-(4-fluorophenyl)-indol-3-yl]-1-piperidyl]ethyl]imidazolidin-2-one::CHEMBL12713::Sertindole

SMILES: Fc1ccc(cc1)-n1cc(C2CCN(CCN3CCNC3=O)CC2)c2cc(Cl)ccc12

InChI Key: InChIKey=GZKLJWGUPQBVJQ-UHFFFAOYSA-N

Data: 141 KI  34 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 175 hits for monomerid = 50001786   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
D(2) dopamine receptor (Rat)	BDBM50001786 (1-[2-[4-[5-chloro-1-(4-fluorophenyl)-indol-3-yl]-1...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.10	n/a	n/a	n/a	n/a	n/a	n/a
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Serotonin 2 (5-HT2) receptor (Rat)	BDBM50001786 (1-[2-[4-[5-chloro-1-(4-fluorophenyl)-indol-3-yl]-1...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.390	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Alpha-1A/Alpha-1B/Alpha-1D adrenergic receptor (Rat)	BDBM50001786 (1-[2-[4-[5-chloro-1-(4-fluorophenyl)-indol-3-yl]-1...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.40	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rat)	BDBM50001786 (1-[2-[4-[5-chloro-1-(4-fluorophenyl)-indol-3-yl]-1...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.10	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Alpha-1A adrenergic receptor (Rat)	BDBM50001786 (1-[2-[4-[5-chloro-1-(4-fluorophenyl)-indol-3-yl]-1...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.40	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Serotonin 2 (5-HT2) receptor (Rat)	BDBM50001786 (1-[2-[4-[5-chloro-1-(4-fluorophenyl)-indol-3-yl]-1...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.390	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rat)	BDBM50001786 (1-[2-[4-[5-chloro-1-(4-fluorophenyl)-indol-3-yl]-1...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.10	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Serotonin 2 (5-HT2) receptor (Rat)	BDBM50001786 (1-[2-[4-[5-chloro-1-(4-fluorophenyl)-indol-3-yl]-1...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.480	n/a	n/a	n/a	n/a	n/a	n/a
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ATP-binding cassette sub-family C member 4 (Human)	BDBM50001786 (1-[2-[4-[5-chloro-1-(4-fluorophenyl)-indol-3-yl]-1...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.33E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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ATP-binding cassette sub-family C member 2 (Human)	BDBM50001786 (1-[2-[4-[5-chloro-1-(4-fluorophenyl)-indol-3-yl]-1...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.33E+5	n/a	n/a	n/a	n/a	n/a	n/a
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Bile salt export pump (Human)	BDBM50001786 (1-[2-[4-[5-chloro-1-(4-fluorophenyl)-indol-3-yl]-1...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	8.27E+4	n/a	n/a	n/a	n/a	n/a	n/a
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ATP-binding cassette sub-family C member 3 (Human)	BDBM50001786 (1-[2-[4-[5-chloro-1-(4-fluorophenyl)-indol-3-yl]-1...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.33E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rat)	BDBM50001786 (1-[2-[4-[5-chloro-1-(4-fluorophenyl)-indol-3-yl]-1...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.10	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Voltage-dependent L-type calcium channel subunit alpha-1C/alpha-1D/alpha-1F/alpha-1S (Human)	BDBM50001786 (1-[2-[4-[5-chloro-1-(4-fluorophenyl)-indol-3-yl]-1...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	6.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Rat)	BDBM50001786 (1-[2-[4-[5-chloro-1-(4-fluorophenyl)-indol-3-yl]-1...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.390	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Alpha-1A adrenergic receptor (Rat)	BDBM50001786 (1-[2-[4-[5-chloro-1-(4-fluorophenyl)-indol-3-yl]-1...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.40	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rat)	BDBM50001786 (1-[2-[4-[5-chloro-1-(4-fluorophenyl)-indol-3-yl]-1...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.10	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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ATP-dependent translocase ABCB1 (Human)	BDBM50001786 (1-[2-[4-[5-chloro-1-(4-fluorophenyl)-indol-3-yl]-1...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	6.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Human)	BDBM50001786 (1-[2-[4-[5-chloro-1-(4-fluorophenyl)-indol-3-yl]-1...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Human)	BDBM50001786 (1-[2-[4-[5-chloro-1-(4-fluorophenyl)-indol-3-yl]-1...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Human)	BDBM50001786 (1-[2-[4-[5-chloro-1-(4-fluorophenyl)-indol-3-yl]-1...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	14	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Potassium voltage-gated channel subfamily A member 5 (Human)	BDBM50001786 (1-[2-[4-[5-chloro-1-(4-fluorophenyl)-indol-3-yl]-1...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Human)	BDBM50001786 (1-[2-[4-[5-chloro-1-(4-fluorophenyl)-indol-3-yl]-1...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	14	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Human)	BDBM50001786 (1-[2-[4-[5-chloro-1-(4-fluorophenyl)-indol-3-yl]-1...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Human)	BDBM50001786 (1-[2-[4-[5-chloro-1-(4-fluorophenyl)-indol-3-yl]-1...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	14.7	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Human)	BDBM50001786 (1-[2-[4-[5-chloro-1-(4-fluorophenyl)-indol-3-yl]-1...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Human)	BDBM50001786 (1-[2-[4-[5-chloro-1-(4-fluorophenyl)-indol-3-yl]-1...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Human)	BDBM50001786 (1-[2-[4-[5-chloro-1-(4-fluorophenyl)-indol-3-yl]-1...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	14.1	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Human)	BDBM50001786 (1-[2-[4-[5-chloro-1-(4-fluorophenyl)-indol-3-yl]-1...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	14.8	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Human)	BDBM50001786 (1-[2-[4-[5-chloro-1-(4-fluorophenyl)-indol-3-yl]-1...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	14	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Human)	BDBM50001786 (1-[2-[4-[5-chloro-1-(4-fluorophenyl)-indol-3-yl]-1...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.70	n/a	n/a	n/a	n/a	n/a	n/a
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Sodium channel protein type 7 subunit alpha (Human)	BDBM50001786 (1-[2-[4-[5-chloro-1-(4-fluorophenyl)-indol-3-yl]-1...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Voltage-dependent L-type calcium channel subunit alpha-1C/alpha-1D/alpha-1F/alpha-1S (Human)	BDBM50001786 (1-[2-[4-[5-chloro-1-(4-fluorophenyl)-indol-3-yl]-1...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	8.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Human)	BDBM50001786 (1-[2-[4-[5-chloro-1-(4-fluorophenyl)-indol-3-yl]-1...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	14	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Human)	BDBM50001786 (1-[2-[4-[5-chloro-1-(4-fluorophenyl)-indol-3-yl]-1...) Show SMILES Show InChI	GoogleScholar	UniChem		0.140	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Rat)	BDBM50001786 (1-[2-[4-[5-chloro-1-(4-fluorophenyl)-indol-3-yl]-1...) Show SMILES Show InChI	GoogleScholar	UniChem		0.200	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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5-hydroxytryptamine receptor 2C (Human)	BDBM50001786 (1-[2-[4-[5-chloro-1-(4-fluorophenyl)-indol-3-yl]-1...) Show SMILES Show InChI	GoogleScholar	UniChem		0.200	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Rat)	BDBM50001786 (1-[2-[4-[5-chloro-1-(4-fluorophenyl)-indol-3-yl]-1...) Show SMILES Show InChI	GoogleScholar	UniChem		0.200	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Human)	BDBM50001786 (1-[2-[4-[5-chloro-1-(4-fluorophenyl)-indol-3-yl]-1...) Show SMILES Show InChI	GoogleScholar	UniChem		0.300	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Rat)	BDBM50001786 (1-[2-[4-[5-chloro-1-(4-fluorophenyl)-indol-3-yl]-1...) Show SMILES Show InChI	GoogleScholar	UniChem		0.300	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Alpha-1B adrenergic receptor (Golden hamster)	BDBM50001786 (1-[2-[4-[5-chloro-1-(4-fluorophenyl)-indol-3-yl]-1...) Show SMILES Show InChI	GoogleScholar	UniChem		0.330	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Alpha-1B adrenergic receptor (Golden hamster)	BDBM50001786 (1-[2-[4-[5-chloro-1-(4-fluorophenyl)-indol-3-yl]-1...) Show SMILES Show InChI	GoogleScholar	UniChem		0.330	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Alpha-1B adrenergic receptor (Golden hamster)	BDBM50001786 (1-[2-[4-[5-chloro-1-(4-fluorophenyl)-indol-3-yl]-1...) Show SMILES Show InChI	GoogleScholar	UniChem		0.330	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Alpha-1A adrenergic receptor (Bovine)	BDBM50001786 (1-[2-[4-[5-chloro-1-(4-fluorophenyl)-indol-3-yl]-1...) Show SMILES Show InChI	GoogleScholar	UniChem		0.370	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Alpha-1A adrenergic receptor (Bovine)	BDBM50001786 (1-[2-[4-[5-chloro-1-(4-fluorophenyl)-indol-3-yl]-1...) Show SMILES Show InChI	GoogleScholar	UniChem		0.370	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Alpha-1A adrenergic receptor (Bovine)	BDBM50001786 (1-[2-[4-[5-chloro-1-(4-fluorophenyl)-indol-3-yl]-1...) Show SMILES Show InChI	GoogleScholar	UniChem		0.370	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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D(2) dopamine receptor (Rat)	BDBM50001786 (1-[2-[4-[5-chloro-1-(4-fluorophenyl)-indol-3-yl]-1...) Show SMILES Show InChI	GoogleScholar	UniChem		0.380	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Human)	BDBM50001786 (1-[2-[4-[5-chloro-1-(4-fluorophenyl)-indol-3-yl]-1...) Show SMILES Show InChI	GoogleScholar	UniChem		0.380	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Human)	BDBM50001786 (1-[2-[4-[5-chloro-1-(4-fluorophenyl)-indol-3-yl]-1...) Show SMILES Show InChI	GoogleScholar	UniChem		0.390	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rat)	BDBM50001786 (1-[2-[4-[5-chloro-1-(4-fluorophenyl)-indol-3-yl]-1...) Show SMILES Show InChI	GoogleScholar	UniChem		0.450	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair