BDBM50001897 1-(4-Chloro-phenyl)-piperazine::CHEMBL114478::pCPP

SMILES Clc1ccc(cc1)N1CCNCC1

InChI Key InChIKey=UNEIHNMKASENIG-UHFFFAOYSA-N

Data  3 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50001897   

Target5-hydroxytryptamine receptor 3A(RAT)
Virginia Commonwealth University

Curated by PDSP Ki Database
LigandPNGBDBM50001897(1-(4-Chloro-phenyl)-piperazine | CHEMBL114478 | pC...)
Affinity DataKi:  120nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50001897(1-(4-Chloro-phenyl)-piperazine | CHEMBL114478 | pC...)
Affinity DataKi:  1.15E+3nMAssay Description:Binding affinity of the compound towards sigma receptor in guinea pig brain membranes using [3H]-DTG as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 3A/3B/3C/3D/3E(Homo sapiens (Human))
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50001897(1-(4-Chloro-phenyl)-piperazine | CHEMBL114478 | pC...)
Affinity DataKi:  2.16E+3nMAssay Description:Compound was tested for the inhibition of [3H]-GR-65,630 binding to 5-hydroxytryptamine 3 receptor expressed in NG 108-15 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-2 adrenergic receptor(Canis familiaris)
Berlex Laboratories

Curated by ChEMBL
LigandPNGBDBM50001897(1-(4-Chloro-phenyl)-piperazine | CHEMBL114478 | pC...)
Affinity DataIC50:  7.00E+4nMAssay Description:Binding affinity towards Beta-2 adrenergic receptor by displacing [3H]dihydroalprenolol, in partially purified membrane fractions from canine lung ti...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-1 adrenergic receptor(Homo sapiens (Human))
Berlex Laboratories

Curated by ChEMBL
LigandPNGBDBM50001897(1-(4-Chloro-phenyl)-piperazine | CHEMBL114478 | pC...)
Affinity DataIC50:  1.50E+4nMAssay Description:Binding affinity for Beta-1 adrenergic receptor by displacing [3H]dihydroalprenolol, in partially purified membrane fractions from canine ventricular...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed