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BDBM50002167 3-[5-(4-Phenyl-3,6-dihydro-2H-pyridin-1-yl)-pentyl]-1H-indole::CHEMBL419957

SMILES: C(CCN1CCC(=CC1)c1ccccc1)CCc1c[nH]c2ccccc12

InChI Key: InChIKey=RDMGNUHCWDMCMI-UHFFFAOYSA-N

Data: 1 KI  1 IC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50002167   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Dopamine D2 receptor/Serotonin 2 (5-HT2) receptor


(Rattus norvegicus (rat))
BDBM50002167
PNG
(3-[5-(4-Phenyl-3,6-dihydro-2H-pyridin-1-yl)-pentyl...)
Show SMILES C(CCN1CCC(=CC1)c1ccccc1)CCc1c[nH]c2ccccc12
Show InChI InChI=1S/C24H28N2/c1-3-9-20(10-4-1)21-14-17-26(18-15-21)16-8-2-5-11-22-19-25-24-13-7-6-12-23(22)24/h1,3-4,6-7,9-10,12-14,19,25H,2,5,8,11,15-18H2
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KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
13n/an/an/an/an/an/an/an/a



E. Merck Darmstadt

Curated by ChEMBL


Assay Description
Evaluated for its ability to displace tritiated receptor ligand in rat striatal membranes [3H]ADTN, a dopamine agonist


J Med Chem 35: 4020-6 (1992)


Article DOI: 10.1021/jm00100a006
BindingDB Entry DOI: 10.7270/Q2K0736G
More data for this
Ligand-Target Pair
Dopamine D2 receptor and Serotonin 2a receptor (D2 and 5HT2a)


(Rattus norvegicus (rat))
BDBM50002167
PNG
(3-[5-(4-Phenyl-3,6-dihydro-2H-pyridin-1-yl)-pentyl...)
Show SMILES C(CCN1CCC(=CC1)c1ccccc1)CCc1c[nH]c2ccccc12
Show InChI InChI=1S/C24H28N2/c1-3-9-20(10-4-1)21-14-17-26(18-15-21)16-8-2-5-11-22-19-25-24-13-7-6-12-23(22)24/h1,3-4,6-7,9-10,12-14,19,25H,2,5,8,11,15-18H2
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 60n/an/an/an/an/an/a



E. Merck Darmstadt

Curated by ChEMBL


Assay Description
Evaluated for its ability to displace tritiated receptor ligand in rat striatal membranes 3[H]spiperone, a dopamine antagonist


J Med Chem 35: 4020-6 (1992)


Article DOI: 10.1021/jm00100a006
BindingDB Entry DOI: 10.7270/Q2K0736G
More data for this
Ligand-Target Pair