BindingDB logo
myBDB logout

BDBM50002215 2-(1-Benzyl-piperidin-4-yl)-1-(4-trifluoromethyl-phenyl)-ethanol; hydrochloride::CHEMBL543437

SMILES: OC(CC1CCN(Cc2ccccc2)CC1)c1ccc(cc1)C(F)(F)F

InChI Key: InChIKey=CPZOJVSRXNVCFS-UHFFFAOYNA-N

Data: 2 KI  1 IC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50002215   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Sigma non-opioid intracellular receptor 1


(Mus musculus (Mouse))
BDBM50002215
PNG
(2-(1-Benzyl-piperidin-4-yl)-1-(4-trifluoromethyl-p...)
Show SMILES OC(CC1CCN(Cc2ccccc2)CC1)c1ccc(cc1)C(F)(F)F
Show InChI InChI=1/C21H24F3NO/c22-21(23,24)19-8-6-18(7-9-19)20(26)14-16-10-12-25(13-11-16)15-17-4-2-1-3-5-17/h1-9,16,20,26H,10-15H2
PDB

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
6n/an/an/an/an/an/an/an/a



DuPont Pharmaceuticals Company

Curated by ChEMBL


Assay Description
In vitro binding affinity for the mouse sigma opioid receptor


J Med Chem 35: 4344-61 (1992)


Article DOI: 10.1021/jm00101a012
BindingDB Entry DOI: 10.7270/Q28P614G
More data for this
Ligand-Target Pair
Serotonin 2 (5-HT2) receptor


(Mus musculus (Mouse))
BDBM50002215
PNG
(2-(1-Benzyl-piperidin-4-yl)-1-(4-trifluoromethyl-p...)
Show SMILES OC(CC1CCN(Cc2ccccc2)CC1)c1ccc(cc1)C(F)(F)F
Show InChI InChI=1/C21H24F3NO/c22-21(23,24)19-8-6-18(7-9-19)20(26)14-16-10-12-25(13-11-16)15-17-4-2-1-3-5-17/h1-9,16,20,26H,10-15H2
UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
>100n/an/an/an/an/an/an/an/a



DuPont Pharmaceuticals Company

Curated by ChEMBL


Assay Description
In vitro binding affinity for serotonin 5-hydroxytryptamine (5-HT) 2 receptors


J Med Chem 35: 4344-61 (1992)


Article DOI: 10.1021/jm00101a012
BindingDB Entry DOI: 10.7270/Q28P614G
More data for this
Ligand-Target Pair
Dopamine D2 receptor


(Mus musculus (Mouse))
BDBM50002215
PNG
(2-(1-Benzyl-piperidin-4-yl)-1-(4-trifluoromethyl-p...)
Show SMILES OC(CC1CCN(Cc2ccccc2)CC1)c1ccc(cc1)C(F)(F)F
Show InChI InChI=1/C21H24F3NO/c22-21(23,24)19-8-6-18(7-9-19)20(26)14-16-10-12-25(13-11-16)15-17-4-2-1-3-5-17/h1-9,16,20,26H,10-15H2
PDB

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a>1.00E+4n/an/an/an/an/an/a



DuPont Pharmaceuticals Company

Curated by ChEMBL


Assay Description
In vitro binding affinity towards dopamine receptor D2


J Med Chem 35: 4344-61 (1992)


Article DOI: 10.1021/jm00101a012
BindingDB Entry DOI: 10.7270/Q28P614G
More data for this
Ligand-Target Pair