BindingDB PrimarySearch

BDBM50002338 (Thioridazine)10-[2-(1-Methyl-piperidin-2-yl)-ethyl]-2-methylsulfanyl-10H-phenothiazine::10-(2-(1-methylpiperidin-2-yl)ethyl)-2-(methylthio)-10H-phenothiazine::10-[2-(1-Methyl-piperidin-2-yl)-ethyl]-2-methylsulfanyl-10H-phenothiazine::10-[2-(1-Methyl-piperidin-2-yl)-ethyl]-2-methylsulfanyl-10H-phenothiazine (thioridazine)::CHEMBL479::MELLARIL::MELLARIL-S::THIORIDAZINE::TP-21::US9504692, Thioridazine

SMILES: CN1CCCC[C@H]1CCN2c3ccccc3Sc4c2cc(cc4)SC

InChI Key: InChIKey=KLBQZWRITKRQQV-UHFFFAOYSA-N

Data: 126 KI 46 IC50 1 Kd 1 EC50

PDB links: 2 PDB IDs match this monomer.

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 174 hits for monomerid = 50002338
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Proteasome subunit alpha type-6 (Human)	BDBM50002338 (10-[2-(1-Methyl-piperidin-2-yl)-ethyl]-2-methylsul...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	n/a	n/a	1.20E+4	n/a	n/a	7.5	37
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Glutathione S-transferase P/Mucosa-associated lymphoid tissue lymphoma translocation protein 1 (Human)	BDBM50002338 (10-[2-(1-Methyl-piperidin-2-yl)-ethyl]-2-methylsul...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	3.43E+3	n/a	n/a	n/a	n/a	n/a	30
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Replicase polyprotein 1ab (2019-nCoV)	BDBM50002338 (10-[2-(1-Methyl-piperidin-2-yl)-ethyl]-2-methylsul...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	6.69E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Bile salt export pump (Human)	BDBM50002338 (10-[2-(1-Methyl-piperidin-2-yl)-ethyl]-2-methylsul...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	2.43E+4	n/a	n/a	n/a	n/a	n/a	n/a
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D(2) dopamine receptor (Rat)	BDBM50002338 (10-[2-(1-Methyl-piperidin-2-yl)-ethyl]-2-methylsul...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	2.80	n/a	n/a	n/a	n/a	n/a	n/a
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D(1A) dopamine receptor (Rat)	BDBM50002338 (10-[2-(1-Methyl-piperidin-2-yl)-ethyl]-2-methylsul...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	1.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
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D(1A) dopamine receptor (Rat)	BDBM50002338 (10-[2-(1-Methyl-piperidin-2-yl)-ethyl]-2-methylsul...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	17	n/a	n/a	n/a	n/a	n/a	n/a
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D(2) dopamine receptor (Rat)	BDBM50002338 (10-[2-(1-Methyl-piperidin-2-yl)-ethyl]-2-methylsul...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
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Adenosine receptor A1 (Rat)	BDBM50002338 (10-[2-(1-Methyl-piperidin-2-yl)-ethyl]-2-methylsul...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Beta-1 adrenergic receptor (Rat)	BDBM50002338 (10-[2-(1-Methyl-piperidin-2-yl)-ethyl]-2-methylsul...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Beta-2 adrenergic receptor (Rat)	BDBM50002338 (10-[2-(1-Methyl-piperidin-2-yl)-ethyl]-2-methylsul...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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D(1A) dopamine receptor (Rat)	BDBM50002338 (10-[2-(1-Methyl-piperidin-2-yl)-ethyl]-2-methylsul...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	80	n/a	n/a	n/a	n/a	n/a	n/a
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Muscarinic acetylcholine receptor M1/M2/M3/M4/M5 (Rat)	BDBM50002338 (10-[2-(1-Methyl-piperidin-2-yl)-ethyl]-2-methylsul...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
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5-hydroxytryptamine receptor 1A/1B/1D/1F (Rat)	BDBM50002338 (10-[2-(1-Methyl-piperidin-2-yl)-ethyl]-2-methylsul...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	8.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Alpha-1A/Alpha-1B/Alpha-1D adrenergic receptor (Rat)	BDBM50002338 (10-[2-(1-Methyl-piperidin-2-yl)-ethyl]-2-methylsul...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	17	n/a	n/a	n/a	n/a	n/a	n/a
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Alpha-2A adrenergic receptor [16-465]/Alpha-2B adrenergic receptor/Alpha-2C adrenergic receptor (Rat)	BDBM50002338 (10-[2-(1-Methyl-piperidin-2-yl)-ethyl]-2-methylsul...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	1.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Serotonin 2 (5-HT2) receptor (Rat)	BDBM50002338 (10-[2-(1-Methyl-piperidin-2-yl)-ethyl]-2-methylsul...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	60	n/a	n/a	n/a	n/a	n/a	n/a
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Voltage-dependent L-type calcium channel subunit alpha-1C/alpha-1D/alpha-1F/alpha-1S (Human)	BDBM50002338 (10-[2-(1-Methyl-piperidin-2-yl)-ethyl]-2-methylsul...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	3.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Mucosa-associated lymphoid tissue lymphoma translocation protein 1 (Human)	BDBM50002338 (10-[2-(1-Methyl-piperidin-2-yl)-ethyl]-2-methylsul...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	3.43E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Mucosa-associated lymphoid tissue lymphoma translocation protein 1 (Human)	BDBM50002338 (10-[2-(1-Methyl-piperidin-2-yl)-ethyl]-2-methylsul...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	4.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Broad substrate specificity ATP-binding cassette transporter ABCG2 (Human)	BDBM50002338 (10-[2-(1-Methyl-piperidin-2-yl)-ethyl]-2-methylsul...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	6.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Potassium voltage-gated channel subfamily H member 2 (Human)	BDBM50002338 (10-[2-(1-Methyl-piperidin-2-yl)-ethyl]-2-methylsul...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	363	n/a	n/a	n/a	n/a	n/a	n/a
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Muscarinic acetylcholine receptor M1/M2/M3/M4/M5 (Rat)	BDBM50002338 (10-[2-(1-Methyl-piperidin-2-yl)-ethyl]-2-methylsul...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	106	n/a	n/a	n/a	n/a	n/a	n/a
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Alpha-1A/Alpha-1B/Alpha-1D adrenergic receptor (Rat)	BDBM50002338 (10-[2-(1-Methyl-piperidin-2-yl)-ethyl]-2-methylsul...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	65	n/a	n/a	n/a	n/a	n/a	n/a
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Serotonin 2 (5-HT2) receptor (Rat)	BDBM50002338 (10-[2-(1-Methyl-piperidin-2-yl)-ethyl]-2-methylsul...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	18	n/a	n/a	n/a	n/a	n/a	n/a
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D(2) dopamine receptor (Rat)	BDBM50002338 (10-[2-(1-Methyl-piperidin-2-yl)-ethyl]-2-methylsul...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	60	n/a	n/a	n/a	n/a	n/a	n/a
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Gamma-aminobutyric acid receptor subunit gamma-1 (Rat)	BDBM50002338 (10-[2-(1-Methyl-piperidin-2-yl)-ethyl]-2-methylsul...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Histamine H1 receptor (Rat)	BDBM50002338 (10-[2-(1-Methyl-piperidin-2-yl)-ethyl]-2-methylsul...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	99	n/a	n/a	n/a	n/a	n/a	n/a
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Alpha-1A/Alpha-1B/Alpha-1D adrenergic receptor (Rat)	BDBM50002338 (10-[2-(1-Methyl-piperidin-2-yl)-ethyl]-2-methylsul...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	65	n/a	n/a	n/a	n/a	n/a	n/a
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Sigma non-opioid intracellular receptor 1 (Rat)	BDBM50002338 (10-[2-(1-Methyl-piperidin-2-yl)-ethyl]-2-methylsul...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	750	n/a	n/a	n/a	n/a	n/a	n/a
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D(2) dopamine receptor (Rat)	BDBM50002338 (10-[2-(1-Methyl-piperidin-2-yl)-ethyl]-2-methylsul...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	60	n/a	n/a	n/a	n/a	n/a	n/a
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Potassium voltage-gated channel subfamily H member 2 (Human)	BDBM50002338 (10-[2-(1-Methyl-piperidin-2-yl)-ethyl]-2-methylsul...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	35.7	n/a	n/a	n/a	n/a	n/a	n/a
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Potassium voltage-gated channel subfamily H member 2 (Human)	BDBM50002338 (10-[2-(1-Methyl-piperidin-2-yl)-ethyl]-2-methylsul...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	191	n/a	n/a	n/a	n/a	n/a	n/a
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Potassium voltage-gated channel subfamily H member 2 (Human)	BDBM50002338 (10-[2-(1-Methyl-piperidin-2-yl)-ethyl]-2-methylsul...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	33.2	n/a	n/a	n/a	n/a	n/a	n/a
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Pleiotropic ABC efflux transporter of multiple drugs (Baker's yeast)	BDBM50002338 (10-[2-(1-Methyl-piperidin-2-yl)-ethyl]-2-methylsul...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	1.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Potassium voltage-gated channel subfamily H member 2 (Human)	BDBM50002338 (10-[2-(1-Methyl-piperidin-2-yl)-ethyl]-2-methylsul...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	191	n/a	n/a	n/a	n/a	n/a	n/a
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Potassium voltage-gated channel subfamily H member 2 (Human)	BDBM50002338 (10-[2-(1-Methyl-piperidin-2-yl)-ethyl]-2-methylsul...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	363	n/a	n/a	n/a	n/a	n/a	n/a
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Potassium voltage-gated channel subfamily H member 2 (Human)	BDBM50002338 (10-[2-(1-Methyl-piperidin-2-yl)-ethyl]-2-methylsul...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	35.5	n/a	n/a	n/a	n/a	n/a	n/a
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Potassium voltage-gated channel subfamily H member 2 (Human)	BDBM50002338 (10-[2-(1-Methyl-piperidin-2-yl)-ethyl]-2-methylsul...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	95.5	n/a	n/a	n/a	n/a	n/a	n/a
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Potassium voltage-gated channel subfamily H member 2 (Human)	BDBM50002338 (10-[2-(1-Methyl-piperidin-2-yl)-ethyl]-2-methylsul...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	35	n/a	n/a	n/a	n/a	n/a	n/a
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Sodium channel protein type 5 subunit alpha (Human)	BDBM50002338 (10-[2-(1-Methyl-piperidin-2-yl)-ethyl]-2-methylsul...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	1.83E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Voltage-dependent L-type calcium channel subunit alpha-1C (Guinea pig)	BDBM50002338 (10-[2-(1-Methyl-piperidin-2-yl)-ethyl]-2-methylsul...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	1.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Potassium voltage-gated channel subfamily H member 2 (Human)	BDBM50002338 (10-[2-(1-Methyl-piperidin-2-yl)-ethyl]-2-methylsul...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	33	n/a	n/a	n/a	n/a	n/a	n/a
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Voltage-dependent L-type calcium channel subunit alpha-1C (Guinea pig)	BDBM50002338 (10-[2-(1-Methyl-piperidin-2-yl)-ethyl]-2-methylsul...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	1.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Voltage-dependent L-type calcium channel subunit alpha-1C (Human)	BDBM50002338 (10-[2-(1-Methyl-piperidin-2-yl)-ethyl]-2-methylsul...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	1.32E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Albumin (Rat)	BDBM50002338 (10-[2-(1-Methyl-piperidin-2-yl)-ethyl]-2-methylsul...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	n/a	6.69E+3	n/a	n/a	n/a	n/a	n/a
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D(1A)/D(1B)/D(2)/D(3)/D(4) dopamine receptor (Rat)	BDBM50002338 (10-[2-(1-Methyl-piperidin-2-yl)-ethyl]-2-methylsul...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	85	n/a	n/a	n/a	n/a	n/a	n/a
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Sodium channel protein type 1/2/3 subunit alpha (Human)	BDBM50002338 (10-[2-(1-Methyl-piperidin-2-yl)-ethyl]-2-methylsul...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	6.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
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D(2) dopamine receptor (Human)	BDBM50002338 (10-[2-(1-Methyl-piperidin-2-yl)-ethyl]-2-methylsul...) Show SMILES Show InChI	GoogleScholar	UniChem	0.400	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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D(2) dopamine receptor (Human)	BDBM50002338 (10-[2-(1-Methyl-piperidin-2-yl)-ethyl]-2-methylsul...) Show SMILES Show InChI	GoogleScholar	UniChem	0.400	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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