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BDBM50002469 ddTMPNPPDideoxythymidine 5'-[alpha,beta-imido]triphosphate

SMILES: Cc1cn([C@H]2CC[C@@H](OP([O-])(=O)NP([O-])(=O)OP([O-])([O-])=O)O2)c(=O)[nH]c1=O

InChI Key: InChIKey=AHKXZYRQWQLFNO-RNFRBKRXSA-J

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50002469   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Human immunodeficiency virus type 1 reverse transcriptase


(Human immunodeficiency virus 1)
BDBM50002469
PNG
(ddTMPNPPDideoxythymidine 5'-[alpha,beta-imido]trip...)
Show SMILES Cc1cn([C@H]2CC[C@@H](OP([O-])(=O)NP([O-])(=O)OP([O-])([O-])=O)O2)c(=O)[nH]c1=O
Show InChI InChI=1S/C9H16N3O12P3/c1-5-4-12(9(14)10-8(5)13)6-2-3-7(22-6)23-25(15,16)11-26(17,18)24-27(19,20)21/h4,6-7H,2-3H2,1H3,(H,10,13,14)(H2,19,20,21)(H3,11,15,16,17,18)/p-4/t6-,7-/m1/s1
PDB
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PC cid
PC sid
UniChem

Similars

Article
PubMed
1.50E+4n/an/an/an/an/an/an/an/a



University of California

Curated by ChEMBL


Assay Description
The compound was tested for the inhibition of human immunodeficiency virus-1 reverse transcriptase(HIV-1 RT).


J Med Chem 35: 1938-41 (1992)


Article DOI: 10.1021/jm00089a002
BindingDB Entry DOI: 10.7270/Q25B0336
More data for this
Ligand-Target Pair