BDBM50002692 (AZT) 1-(4-Azido-5-hydroxymethyl-tetrahydro-furan-2-yl)-5-methyl-1H-pyrimidine-2,4-dione::(AZT)1-(4-Azido-5-hydroxymethyl-tetrahydro-furan-2-yl)-5-methyl-1H-pyrimidine-2,4-dione::1-((2R,4R,5S)-4-azido-5-(hydroxymethyl)tetrahydrofuran-2-yl)-5-methylpyrimidine-2,4(1H,3H)-dione::1-((2R,4S,5S)-4-(diazoamino)-5-(hydroxymethyl)-tetrahydrofuran-2-yl)-5-methylpyrimidine-2,4(1H,3H)-dione::1-((2R,4S,5S)-4-Azido-5-hydroxymethyl-tetrahydro-furan-2-yl)-5-methyl-1H-pyrimidine-2,4-dione::1-((2R,4S,5S)-4-azido-5-(hydroxymethyl)-tetrahydrofuran-2-yl)-5-methylpyrimidine-2,4(1H,3H)-dione::1-((2R,4S,5S)-4-azido-5-(hydroxymethyl)tetrahydrofuran-2-yl)-5-methylpyrimidine-2,4(1H,3H)-dione::1-((2R,5S)-4-Azido-5-hydroxymethyl-tetrahydro-furan-2-yl)-5-methyl-1H-pyrimidine-2,4-dione::1-((2S,4R,5R)-4-Azido-5-hydroxymethyl-tetrahydro-furan-2-yl)-5-methyl-1H-pyrimidine-2,4-dione::1-(4-Azido-5-hydroxymethyl-tetrahydro-furan-2-yl)-5-methyl-1H-pyrimidine-2,4-dione::1-(4-Azido-5-hydroxymethyl-tetrahydro-furan-2-yl)-5-methyl-1H-pyrimidine-2,4-dione (AZT)::1-(4-Azido-5-hydroxymethyl-tetrahydro-furan-2-yl)-5-methyl-1H-pyrimidine-2,4-dione (AzddThd, AZT)::1-(4-Azido-5-hydroxymethyl-tetrahydro-furan-2-yl)-5-methyl-1H-pyrimidine-2,4-dione (N3ddThd)::1-(4-Azido-5-hydroxymethyl-tetrahydro-furan-2-yl)-5-methyl-1H-pyrimidine-2,4-dione [AZT]::1-(4-Azido-5-hydroxymethyl-tetrahydro-furan-2-yl)-5-methyl-1H-pyrimidine-2,4-dione(3'-azido-2',3'-dideoxythymidine)::1-(4-Azido-5-hydroxymethyl-tetrahydro-furan-2-yl)-5-methyl-1H-pyrimidine-2,4-dione(AZT)::1-(4-Azido-5-hydroxymethyl-tetrahydro-furan-2-yl)-5-methyl-1H-pyrimidine-2,4-dione(Zidovudine, AZT)::1-(4-Azido-5-hydroxymethyl-tetrahydro-furan-2-yl)-5-methyl-1H-pyrimidine-2,4-dione(azidothymidine, AZT)::3'-Azido-3'-deoxy-thymidine::3'-Deoxy-3-azidothymidine::3'-azido-2',3'-dideoxythymidine::3'-azido-thymidine::3'azido-2'3'-dideoxythymidine::3-((2S,3S,5R)-2-(hydroxymethyl)-5-(5-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)tetrahydrofuran-3-yl)triaz-1-en-2-ium-1-ide::4-(4-Azido-5-hydroxy-tetrahydro-furan-2-yl)-5-methyl-3H-pyrazine-2,6-dione::AZT::BW-A-509U::BWA509U::CHEMBL129::Retrovir::US10071110, Compound AZT::US11420959, Example AZT::ZIDOVUDINE::azidothymidine::zidovudin::zudovidine

SMILES: CC1=CN(C(=O)NC1=O)[C@H]2C[C@@H]([C@H](O2)CO)N=[N+]=[N-]

InChI Key: InChIKey=HBOMLICNUCNMMY-UHFFFAOYSA-N

Data: 10 KI  36 IC50  2 Kd  21 EC50

PDB links: 5 PDB IDs match this monomer.

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 69 hits for monomerid = 50002692   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
C-X-C chemokine receptor type 4 (Human)	BDBM50002692 (1-((2R,4S,5S)-4-Azido-5-hydroxymethyl-tetrahydro-f...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	7.90	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Gag-Pol polyprotein [489-587] (Human immunodeficiency virus type 1)	BDBM50002692 (1-((2R,4S,5S)-4-Azido-5-hydroxymethyl-tetrahydro-f...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	126	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Reverse transcriptase (Human immunodeficiency virus type 1)	BDBM50002692 (1-((2R,4S,5S)-4-Azido-5-hydroxymethyl-tetrahydro-f...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	12.7	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus type 1)	BDBM50002692 (1-((2R,4S,5S)-4-Azido-5-hydroxymethyl-tetrahydro-f...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus type 1)	BDBM50002692 (1-((2R,4S,5S)-4-Azido-5-hydroxymethyl-tetrahydro-f...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Envelope glycoprotein gp160 (HIV-1)	BDBM50002692 (1-((2R,4S,5S)-4-Azido-5-hydroxymethyl-tetrahydro-f...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	3	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus type 1)	BDBM50002692 (1-((2R,4S,5S)-4-Azido-5-hydroxymethyl-tetrahydro-f...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus type 1)	BDBM50002692 (1-((2R,4S,5S)-4-Azido-5-hydroxymethyl-tetrahydro-f...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus type 1)	BDBM50002692 (1-((2R,4S,5S)-4-Azido-5-hydroxymethyl-tetrahydro-f...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus type 1)	BDBM50002692 (1-((2R,4S,5S)-4-Azido-5-hydroxymethyl-tetrahydro-f...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Protein kinase C beta type (Human)	BDBM50002692 (1-((2R,4S,5S)-4-Azido-5-hydroxymethyl-tetrahydro-f...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.50E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Protein kinase C epsilon type (Human)	BDBM50002692 (1-((2R,4S,5S)-4-Azido-5-hydroxymethyl-tetrahydro-f...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.50E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
DNA polymerase beta (Human)	BDBM50002692 (1-((2R,4S,5S)-4-Azido-5-hydroxymethyl-tetrahydro-f...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Thymidine kinase (Ureaplasma parvum)	BDBM50002692 (1-((2R,4S,5S)-4-Azido-5-hydroxymethyl-tetrahydro-f...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.25E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Thymidine kinase, cytosolic (Human)	BDBM50002692 (1-((2R,4S,5S)-4-Azido-5-hydroxymethyl-tetrahydro-f...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus type 1)	BDBM50002692 (1-((2R,4S,5S)-4-Azido-5-hydroxymethyl-tetrahydro-f...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	3	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus type 1)	BDBM50002692 (1-((2R,4S,5S)-4-Azido-5-hydroxymethyl-tetrahydro-f...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	40	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus type 1)	BDBM50002692 (1-((2R,4S,5S)-4-Azido-5-hydroxymethyl-tetrahydro-f...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	10	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus type 1)	BDBM50002692 (1-((2R,4S,5S)-4-Azido-5-hydroxymethyl-tetrahydro-f...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	2.49E+4	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus type 1)	BDBM50002692 (1-((2R,4S,5S)-4-Azido-5-hydroxymethyl-tetrahydro-f...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	38	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
C-X-C chemokine receptor type 4 (Human)	BDBM50002692 (1-((2R,4S,5S)-4-Azido-5-hydroxymethyl-tetrahydro-f...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	48	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus type 1)	BDBM50002692 (1-((2R,4S,5S)-4-Azido-5-hydroxymethyl-tetrahydro-f...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	3	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus type 1)	BDBM50002692 (1-((2R,4S,5S)-4-Azido-5-hydroxymethyl-tetrahydro-f...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	2	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus type 1)	BDBM50002692 (1-((2R,4S,5S)-4-Azido-5-hydroxymethyl-tetrahydro-f...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	8	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus type 1)	BDBM50002692 (1-((2R,4S,5S)-4-Azido-5-hydroxymethyl-tetrahydro-f...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	3	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus type 1)	BDBM50002692 (1-((2R,4S,5S)-4-Azido-5-hydroxymethyl-tetrahydro-f...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	3	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus type 1)	BDBM50002692 (1-((2R,4S,5S)-4-Azido-5-hydroxymethyl-tetrahydro-f...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	3	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Reverse transcriptase (Human immunodeficiency virus type 1)	BDBM50002692 (1-((2R,4S,5S)-4-Azido-5-hydroxymethyl-tetrahydro-f...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.82E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Albumin (Human)	BDBM50002692 (1-((2R,4S,5S)-4-Azido-5-hydroxymethyl-tetrahydro-f...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	4.40E+4	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Reverse transcriptase (Human immunodeficiency virus type 1)	BDBM50002692 (1-((2R,4S,5S)-4-Azido-5-hydroxymethyl-tetrahydro-f...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.01E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus type 1)	BDBM50002692 (1-((2R,4S,5S)-4-Azido-5-hydroxymethyl-tetrahydro-f...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.10	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
HIV-1 protease (Human immunodeficiency virus)	BDBM50002692 (1-((2R,4S,5S)-4-Azido-5-hydroxymethyl-tetrahydro-f...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	7	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Gag-Pol polyprotein (HIV-1)	BDBM50002692 (1-((2R,4S,5S)-4-Azido-5-hydroxymethyl-tetrahydro-f...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	49	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
ATP-binding cassette sub-family C member 4 (Human)	BDBM50002692 (1-((2R,4S,5S)-4-Azido-5-hydroxymethyl-tetrahydro-f...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.33E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
ATP-binding cassette sub-family C member 3 (Human)	BDBM50002692 (1-((2R,4S,5S)-4-Azido-5-hydroxymethyl-tetrahydro-f...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.33E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
ATP-binding cassette sub-family C member 2 (Human)	BDBM50002692 (1-((2R,4S,5S)-4-Azido-5-hydroxymethyl-tetrahydro-f...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.33E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Bile salt export pump (Human)	BDBM50002692 (1-((2R,4S,5S)-4-Azido-5-hydroxymethyl-tetrahydro-f...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.33E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus type 1)	BDBM50002692 (1-((2R,4S,5S)-4-Azido-5-hydroxymethyl-tetrahydro-f...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Reverse transcriptase (Human immunodeficiency virus type 1)	BDBM50002692 (1-((2R,4S,5S)-4-Azido-5-hydroxymethyl-tetrahydro-f...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	7	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Reverse transcriptase (Human immunodeficiency virus type 1)	BDBM50002692 (1-((2R,4S,5S)-4-Azido-5-hydroxymethyl-tetrahydro-f...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	17	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Reverse transcriptase (Human immunodeficiency virus type 1)	BDBM50002692 (1-((2R,4S,5S)-4-Azido-5-hydroxymethyl-tetrahydro-f...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	8.90	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Reverse transcriptase (Human immunodeficiency virus type 1)	BDBM50002692 (1-((2R,4S,5S)-4-Azido-5-hydroxymethyl-tetrahydro-f...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	6.60	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Reverse transcriptase (Human immunodeficiency virus type 1)	BDBM50002692 (1-((2R,4S,5S)-4-Azido-5-hydroxymethyl-tetrahydro-f...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Reverse transcriptase (Human immunodeficiency virus type 1)	BDBM50002692 (1-((2R,4S,5S)-4-Azido-5-hydroxymethyl-tetrahydro-f...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Reverse transcriptase (Human immunodeficiency virus type 1)	BDBM50002692 (1-((2R,4S,5S)-4-Azido-5-hydroxymethyl-tetrahydro-f...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Reverse transcriptase (Human immunodeficiency virus type 1)	BDBM50002692 (1-((2R,4S,5S)-4-Azido-5-hydroxymethyl-tetrahydro-f...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Reverse transcriptase (Human immunodeficiency virus type 1)	BDBM50002692 (1-((2R,4S,5S)-4-Azido-5-hydroxymethyl-tetrahydro-f...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.54E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus type 1)	BDBM50002692 (1-((2R,4S,5S)-4-Azido-5-hydroxymethyl-tetrahydro-f...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus type 1)	BDBM50002692 (1-((2R,4S,5S)-4-Azido-5-hydroxymethyl-tetrahydro-f...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus type 1)	BDBM50002692 (1-((2R,4S,5S)-4-Azido-5-hydroxymethyl-tetrahydro-f...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	17	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair