BDBM50002776 11-[2-(2-Nitro-benzenesulfonylamino)-ethylsulfanyl]-6,11-dihydro-dibenzo[b,e]oxepine-2-carboxylic acid::CHEMBL444330

SMILES OC(=O)c1ccc2OCc3ccccc3C(SCCNS(=O)(=O)c3ccccc3[N+]([O-])=O)c2c1

InChI Key InChIKey=XBRIDFAVLXDLOQ-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50002776   

TargetThromboxane A2 receptor(Homo sapiens (Human))
Kyowa Hakko Kogyo

Curated by ChEMBL
LigandPNGBDBM50002776(11-[2-(2-Nitro-benzenesulfonylamino)-ethylsulfanyl...)
Affinity DataKi:  15nMAssay Description:Inhibition of Shh signaling in mouse Shh-light2 cells by Gli-dependent firefly luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThromboxane A2 receptor(Homo sapiens (Human))
Kyowa Hakko Kogyo

Curated by ChEMBL
LigandPNGBDBM50002776(11-[2-(2-Nitro-benzenesulfonylamino)-ethylsulfanyl...)
Affinity DataKi:  15nMAssay Description:Binding affinity at TXA2 receptor by measuring its ability to displace [3H]-U-46,619 from guinea pig plateletsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed