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BDBM50003344 3-Propyl-2,3,4,5-tetrahydro-1H-benzo[d]azepin-7-ol::CHEMBL129676

SMILES: CCCN1CCc2ccc(O)cc2CC1

InChI Key: InChIKey=RZURICYHBFWBJM-UHFFFAOYSA-N

Data: 2 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50003344   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Dopamine D2 receptor/Serotonin 2 (5-HT2) receptor


(Rattus norvegicus (rat))
BDBM50003344
PNG
(3-Propyl-2,3,4,5-tetrahydro-1H-benzo[d]azepin-7-ol...)
Show SMILES CCCN1CCc2ccc(O)cc2CC1
Show InChI InChI=1S/C13H19NO/c1-2-7-14-8-5-11-3-4-13(15)10-12(11)6-9-14/h3-4,10,15H,2,5-9H2,1H3
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KEGG

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PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 1.00E+4n/an/an/an/an/an/a



University of Göteborg

Curated by ChEMBL


Assay Description
Inhibitory activity against Dopamine receptor D2 in rats using [3H]-spiperone as radioligand


J Med Chem 35: 3984-90 (1992)


Article DOI: 10.1021/jm00100a002
BindingDB Entry DOI: 10.7270/Q2QN65QF
More data for this
Ligand-Target Pair
Serotonin (5-HT) receptor


(Rattus norvegicus (rat))
BDBM50003344
PNG
(3-Propyl-2,3,4,5-tetrahydro-1H-benzo[d]azepin-7-ol...)
Show SMILES CCCN1CCc2ccc(O)cc2CC1
Show InChI InChI=1S/C13H19NO/c1-2-7-14-8-5-11-3-4-13(15)10-12(11)6-9-14/h3-4,10,15H,2,5-9H2,1H3
KEGG

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 4.00E+3n/an/an/an/an/an/a



University of Göteborg

Curated by ChEMBL


Assay Description
Inhibitory activity against 5-hydroxytryptamine 1A receptor in rats, using [3H]-8-OH-DPAT as radioligand


J Med Chem 35: 3984-90 (1992)


Article DOI: 10.1021/jm00100a002
BindingDB Entry DOI: 10.7270/Q2QN65QF
More data for this
Ligand-Target Pair