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BDBM50003413 1-(biphenyl)-3-benzyl-3-acetyloxyamino-propenone::CHEMBL130334

SMILES: CC(=O)ON(Cc1ccccc1)C=CC(=O)c1ccc(cc1)-c1ccccc1

InChI Key: InChIKey=XNJNIOGSNJYFTB-MSUUIHNZSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50003413   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Arachidonate 5-lipoxygenase


(Rattus norvegicus)
BDBM50003413
PNG
(1-(biphenyl)-3-benzyl-3-acetyloxyamino-propenone |...)
Show SMILES CC(=O)ON(Cc1ccccc1)C=CC(=O)c1ccc(cc1)-c1ccccc1
Show InChI InChI=1S/C24H21NO3/c1-19(26)28-25(18-20-8-4-2-5-9-20)17-16-24(27)23-14-12-22(13-15-23)21-10-6-3-7-11-21/h2-17H,18H2,1H3/b17-16-
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a>2.50E+4n/an/an/an/an/an/a



DuPont Pharmaceuticals Company

Curated by ChEMBL


Assay Description
inhibitory activity against 5-lipoxygenase in rat basophilic leukemia cell line.


J Med Chem 35: 4061-8 (1992)


Article DOI: 10.1021/jm00100a011
BindingDB Entry DOI: 10.7270/Q2BC3XHJ
More data for this
Ligand-Target Pair