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BDBM50003433 3-Benzyloxyamino-1-biphenyl-4-yl-propenone::CHEMBL334528

SMILES: O=C(CC=NOCc1ccccc1)c1ccc(cc1)-c1ccccc1

InChI Key: InChIKey=PAFORHWBCBEMJD-XQNSMLJCSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50003433   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Arachidonate 5-lipoxygenase


(Rattus norvegicus)
BDBM50003433
PNG
(3-Benzyloxyamino-1-biphenyl-4-yl-propenone | CHEMB...)
Show SMILES O=C(CC=NOCc1ccccc1)c1ccc(cc1)-c1ccccc1
Show InChI InChI=1S/C22H19NO2/c24-22(15-16-23-25-17-18-7-3-1-4-8-18)21-13-11-20(12-14-21)19-9-5-2-6-10-19/h1-14,16H,15,17H2/b23-16+
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a>2.50E+4n/an/an/an/an/an/a



Du Pont Merck Pharmaceutical Company

Curated by ChEMBL


Assay Description
inhibitory activity against 5-lipoxygenase in rat basophilic leukemia cell line.


J Med Chem 35: 4061-8 (1992)


Article DOI: 10.1021/jm00100a011
BindingDB Entry DOI: 10.7270/Q2BC3XHJ
More data for this
Ligand-Target Pair